• Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom 

      Escalante Muñoz, Teresa; Núñez, Javier; Moura Da Silva, Ana M.; Rucavado Romero, Alexandra; Theakston, R. David G.; Gutiérrez, José María (2003-11-15)
      Jararhagin is the most important hemorrhagic component in the venom of the snake Bothrops jararaca, a species of medical importance in South America. It is a P-III zinc-dependent metalloproteinase comprising catalytic, ...
    • Snake venom metalloproteinases: structure/function relationships studies using monoclonal antibodies 

      Tanjoni, Isabelle; Butera, Diego; Bento, Luciana; Della Casa, Maisa S.; Marques Porto, Rafael; Takehara, Harumi Ando; Gutiérrez, José María; Fernandes, Irene; Moura Da Silva, Ana M. (2003-12)
      Snake Venom Metalloproteinases (SVMPs) are synthesized as zymogens and undergo proteolytic processing resulting in a variety of multifunctional proteins. Jararhagin is a P-III SVMP, isolated from the venom of Bothrops ...