Now showing items 1-20 of 10160

    • 1,1-Diphenyl-4-(thiophen-2-yl)but-3-yn-1-ol 

      Umaña, Christian A.; Pineda Cedeño, Leslie William; Cabezas Pizarro, Jorge A. (2018-11)
      The asymmetric unit of the title homopropargyl alcohol, C20H16OS, contains two independent molecules comprising a hydroxy group, a 3-(2-thiophenyl)- propargylic moiety and two aromatic rings linked to a central carbon atom. ...
    • 1998 

      Programa Cooperativo Regional de Frijol para Centroamérica, México y el Caribe (PROFRIJOL) (Universidad de Costa Rica, 1997)
    • 1998 

      Programa Cooperativo Regional de Frijol para Centroamérica, México y el Caribe (PROFRIJOL) (Universidad de Costa Rica, 1998)
    • 1999 

      Programa Cooperativo Regional de Frijol para Centroamérica, México y el Caribe (PROFRIJOL) (Universidad de Costa Rica, 1999)
    • 20 años de Estam/Pasión 1989-2009 

      Murillo Herrera, Alberto (SIEDIN, 2009-07-02)
      Catálogo de la exposición retrospectiva, realizada en el Instituto de México en San José, en julio de 2009. Es una muestra representativa de veinte años de producción artística. Reúne más de setenta obras del artista, ...
    • ¡200 Petabytes a 100 Megadólares!: Surá – Clúster para el almacenamiento y procesamiento de datos científicos del PRIS-LAB. 

      Siles Canales, Francisco; Calderón Ramírez, Saúl; Villalta Fallas, Marco (2014-01-10)
      Póster presentado en la III Conferencia Internacional de Acceso Abierto, Preservación Digital y Datos científicos (Biredial-SIBD) 15-17 de octubre de 2013. El desarrollo de sistemas computacionales más poderosos en la ...
    • 25 Years of the Internet in Central America: an interview with Guy de Téramond 

      Siles González, Ignacio (2017-10)
      January 2018 marks the 25th anniversary of the first dedicated Internet connection in Central America. Little is known about the conditions that characterised the early development of the Internet in this part of the globe. ...
    • 50 años de la carrera de Bibliotecología en Costa Rica 

      Vargas Bormón, Marlon; Vargas Rodríguez, Mónica; Cruz Zuñiga, Alejandra; Guadamuz Villalobos, Jairo Andrés (2018-03-21)
      El documental realiza un recorrido histórico que inicia con la creación de las primeras bibliotecas en el país, en manos de Miguel Obregón Lizano, y finaliza en el 2018, repasando lugares, momentos históricos y protagonistas ...
    • A 70 años de la Nakba, la paz nunca ha brillado tanto por su ausencia 

      Johanning Solís, Javier José (2018)
      El artículo pretende contextualizar el conflicto palestino-israelí en el 70 aniversario de la Nakba o catástrofe, su desarrollo y estado actual, a partir del plan de paz ideado por la Administración Trump. La Nakba o ...
    • A BDDC algorithm with deluxe scaling for H(curl) in two dimensions with irregular subdomains 

      Calvo Alpízar, Juan Gabriel (2015)
      A bound is obtained for the condition number of a BDDC algorithm for problems posed in H(curl) in two dimensions, where the subdomains are only assumed to be uniform in the sense of Peter Jones. For the primal variable ...
    • A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation 

      Acón, Man Sai; Siles Canales, Francisco; Mora Rodríguez, Rodrigo (2016-11-09)
      Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ...
    • A bright future for integrative venomics 

      Calvete Chornet, Juan José; Lomonte, Bruno (2015-10)
      Venomous secretions are produced by a myriad of animal species, from invertebrates to vertebrates. As a general rule, peptides and proteins represent the most abundant and functionally relevant components of these dangerous ...
    • A Call for Incorporating Social Research in the Global Struggle against Snakebite 

      Gutiérrez, José María; Burnouf, Thierry; Harrison, Robert A.; Calvete Chornet, Juan José; Brown, Nicholas I.; Jensen, Simon D.; Warrell, David A.; Williams, David J. (2015-09-17)
      In Africa, Asia, Latin America, and parts of Oceania, envenoming after snakebite is a serious public health problem. Conservative data suggest that between 1.2 and 5.5 million people suffer snakebites every year, resulting ...
    • A call-and-response system facilitates group cohesion among disc-winged bats 

      Chaverri Echandi, Gloriana; Gillam, Erin H.; Kunz, Thomas H. (2013)
      Acoustic signals are important in maintaining group cohesion, particularly in highly mobile species. For these signals to facilitate group cohesion, individuals must be able to recognize, and respond to, calls emitted by ...
    • A carbonate platform associated with shallow cold methane seeps in Golfo Dulce, Pacific Costa Rica 

      Wild, Christian; Rixen, Tim; Sánchez Noguera, Celeste; Merico, Agostino; Jiménez Centeno, Carlos; Cortés Núñez, Jorge; Naumann, Malik S. (2015)
      Marine methane seeps are typically observed in cold, anoxic and organic-rich deep-sea environments, such as in the Black Sea, where methane emissions fuel the authigenic accretion of calcium carbonate structures via microbial ...
    • A case-control study of breast cancer and hormonal contraception in Costa Rica 

      Rosero Bixby, Luis; Grimaldo Vásquez, Carmen; Rovira, Elizabeth; Lee, Nancy C.; Oberle, Mark W.; Watley, Anne S. (1987)
      By 1981, 11% of married women in Costa Rica ages 20-49 years had used depot-medroxyprogesterone acetate (DMPA) and 58% had used oral contraceptives (OCs). Since 1977, the Costa Rican Ministry of Health has maintained a ...
    • A catalytically-inactive snake venom Lys49 phospholipase A2 homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages 

      Moreira, Vanessa; de Castro Souto, Pollyana Cristina Maggio; Ramirez Vinolo, Marco Aurélio; Lomonte, Bruno; Gutiérrez, José María; Curi, Rui; Teixeira, Catarina de Fátima (2013-05-15)
      The effects of a snakevenom Lys-49phospholipaseA2 (PLA2) homolog named MT-II,devoid of enzymatic activity, on the biosynthesis of prostaglandins and protein expression of cyclooxygenase-2(COX-2) and signaling pathways ...
    • A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C 

      Flores Díaz, Marietta; Alape Girón, Alberto; Clark, Graeme; Catimel, Bruno; Hirabayashi, Yoshio; Nice, Ed; Gutiérrez, José María; Titball, Richard; Thelestam, Mónica (2005-07-22)
      Clostridium perfringens phospholipase C (Cp-PLC), also called alpha-toxin, is the major virulence factor in the pathogenesis of gas gangrene. Previously, a cellular UDP-Glc deficiency was related with a hypersensitivity ...
    • A check list of asexual fungi from Costa Rica 

      Granados Montero, María del Milagro; Minter, David William; Castañeda Ruiz, Rafael F. (2018-09-27)
      A checklist of recorded asexual fungi from Costa Rica is presented. This study compiles information from 1927 to 2018 based on scientific papers, theses, reviews of hyphomycetous and coelomycetous fungi, dermatophyte ...
    • A climate change projection for summer hydrologic conditions in a semiarid watershed of central Arizona 

      Hawkins, Gretchen A.; Vivoni, Enrique R.; Robles Morua, Agustin; Mascaro, Giuseppe; Rivera Fernández, Erick; Dominguez, Francina (2015-03-05)
      Potential climate change impacts on summer precipitation and subsequent hydrologic responses in the southwestern U.S. are poorly constrained at present due to a lack of studies accounting for high resolution processes. In ...