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First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis 

Lomonte, Bruno; Mora Obando, Diana; Fernández Ulate, Julián; Sanz, Libia; Pla Ferrer, Davinia; Gutiérrez, José María; Calvete Chornet, Juan José (Toxicon vol 93:144–154, 2015-01)
Bothriechis nigroviridis is an arboreal Neotropical pitviper found in Costa Rica and Panam a. A previous proteomic profiling of its venom revealed the presence of proteins with homology to the A and B subunits of ...
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Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming 

Gutiérrez, José María; Lomonte, Bruno; León Montero, Guillermo; Alape Girón, Alberto; Flores Díaz, Marietta; Sanz, Libia; Angulo Ugalde, Yamileth; Calvete Chornet, Juan José (2009-03-06)
Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact, particularly in Asia, Africa and Latin America. A global initiative, aimed at increasing antivenom production and ...

Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids 

Fernández Ulate, Julián; Vargas Vargas, Nancy; Pla Ferrer, Davinia; Sasa Marín, Mahmood; Rey Suárez, Paola; Sanz, Libia; Gutiérrez, José María; Calvete Chornet, Juan José; Lomonte, Bruno (2015-12-01)
Protein composition, toxicity, and neutralization of the venoms of Micrurus alleni and Micrurus mosquitensis, two sympatric monadal coral snakes found in humid environments of the Caribbean region of Costa Rica, were ...
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Snake Venomics and Antivenomics of the Arboreal Neotropical Pitvipers Bothriechis lateralis and Bothriechis schlegelii 

Lomonte, Bruno; Escolano, José; Fernández Ulate, Julián; Sanz, Libia; Angulo Ugalde, Yamileth; Gutiérrez, José María; Calvete Chornet, Juan José (2008-04-30)
We report the comparative proteomic characterization of the venoms of two related neotropical arboreal pitvipers from Costa Rica of the genus Bothriechis, B. lateralis (side-striped palm pit viper) and B. schlegelii (eyelash ...

Snake Venomics of Central American Pitvipers: Clues for Rationalizing the Distinct Envenomation Profiles of Atropoides nummifer and Atropoides picadoi 

Angulo Ugalde, Yamileth; Escolano, José; Lomonte, Bruno; Gutiérrez, José María; Sanz, Libia; Calvete Chornet, Juan José (2008)
We report the proteomic characterization of the Central American pitvipers Atropoides nummifer and Atropoides picadoi. The crude venoms were fractionated by reverse-phase high-performance liquid chromatography (HPLC), ...
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Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization 

Fernández Ulate, Julián; Gutiérrez, José María; Angulo Ugalde, Yamileth; Sanz, Libia; Juárez, Paula; Calvete Chornet, Juan José; Lomonte, Bruno (2010-03)
Phospholipases A2 (PLA2) are major components of snake venoms, exerting a variety of relevant toxic actions such as neurotoxicity and myotoxicity, among others. Since the majority of toxic PLA2s are basic proteins, acidic ...
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Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing 

Durban, Jordi; Juárez, Paula; Angulo Ugalde, Yamileth; Lomonte, Bruno; Flores Díaz, Marietta; Alape Girón, Alberto; Sasa Marín, Mahmood; Sanz, Libia; Gutiérrez, José María; Dopazo, Joaquín; Conesa, Ana; Calvete Chornet, Juan José (BMC Genomics, 12:259, 2011, 2011)
Background: A long term research goal of venomics, of applied importance for improving current antivenom therapy, but also for drug discovery, is to understand the pharmacological potential of venoms. Individually ...
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Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms 

Calvete Chornet, Juan José; Sanz, Libia; Pla Ferrer, Davinia; Lomonte, Bruno; Gutiérrez, José María (Toxins vol.6:3388-3405, 2014-12-15)
Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact worldwide, mostly affecting poor people involved in agricultural activities in Africa, Asia, Latin America and Oceania. A ...
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Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics 

Lomonte, Bruno; Fernández Ulate, Julián; Sanz, Libia; Angulo Ugalde, Yamileth; Sasa Marín, Mahmood; Gutiérrez, José María; Calvete Chornet, Juan José (Journal of Proteomics XX (2014) XXX – XXX, Available online 24 February 2014, 2014-02-24)
In spite of its small territory of ~50,000 km2, Costa Rica harbors a remarkably rich biodiversity. Its herpetofauna includes 138 species of snakes, of which sixteen pit vipers (family Viperidae, subfamily Crotalinae), five ...
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Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays 

Gutiérrez, José María; Lomonte, Bruno; Sanz, Libia; Calvete Chornet, Juan José; Pla Ferrer, Davinia (En prensa, 2014-02-28)
Parenteral administration of animal-derived antivenoms constitutes the mainstay in the treatment of snakebite envenomings. Despite the fact that this therapy has been available for over a century, the detailed understanding ...
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AuthorCalvete Chornet, Juan José (30)
Lomonte, Bruno (30)
Sanz, Libia (30)
Gutiérrez, José María (27)Angulo Ugalde, Yamileth (16)Fernández Ulate, Julián (11)Pla Ferrer, Davinia (10)Pérez, Alicia (7)Alape Girón, Alberto (5)Sasa Marín, Mahmood (5)... View MoreType
Artículo científico (30)
info:eu-repo/semantics/article (30)
ProcedenceVicerrectoría de Investigación (30)Vicerrectoría de Docencia (3)... View MoreHas File(s)Yes (30)

  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
  • Biblioteca Digital del CIICLA
  • Repositorio Documental Rafael Obregón Loría (CIHAC)
  • Biblioteca Digital Carlos Melendez (CIHAC)
  • Repositorio de Fotografías
  • Colección de videos de UPA-VAS
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  • Buscador regional de LA Referencia
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  • @Ciencia_UCR
  • Sobre Kérwá
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Contact Us | Send Feedback
Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica