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Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
(2008)
Dawley rats were reared from weaning in either social isolation, standard laboratory conditions, or environmental enrichment. Open-field activity
was assessed at postnatal days 37, 65, 93 and 107 and 1 h before the last ...
Maternal behavior as an early modulator of neurobehavioral offspring responses by Sprague-Dawley rats
(2013)
Maternal care plays an important role as an early modeler of neurodevelopment and brain function,
and its effects remain until adulthood. Such modeling or programming has shown to influence the
stress response and ...
The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum
(2009-03-02)
This study examined the effect of fluoxetine, a selective serotonin (5-HT) reuptake inhibitor, on isolation-induced changes on sucrose consumption and preference, spontaneous open-field activity, forced swimming behavior, ...
Behavioral and neurochemical characterization of maternal care effects on juvenile Sprague–Dawley rats
(2013)
Maternal care represents a major constituent of early life environment and has the potential to modulate critical
neurobehavioral responses to stress. The aim of the present study was to determine the effects of naturally ...
Ejercicio y algunos mecanismos moleculares que subyacen a una mejora del desempeño en tareas cognitivas
Exercise and some molecular mechanisms that underlie performance increase on cognitive tasks
(2020)
Potenciar el aprendizaje y la memoria se ha convertido en una tarea de
interés para muchos investigadores. Artículos recientes han podido comprobar
que el ejercicio es una clara herramienta para mejorar capacidades ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
(2017-05-30)
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Un método simple para la recolección, extracción y medición de catecolaminas en orina de adultos mayores
A simple method to collect, extract and measure urinary catecholamines in elderly people
(2007)
La medición de catecolaminas en orina ha sido utilizada tanto para diagnóstico
como para la investigación. Este trabajo propone algunas modificaciones
y condiciones estandarizadas para llevar a cabo la recolección ...
Environmental Enrichment and Physical Exercise Attenuate the Depressive-Like Effects Induced by Social Isolation Stress in Rats
(2020)
We assessed the antidepressant-like effects of environmental enrichment (EE) and
physical exercise (PE) compared with the selective serotonin reuptake inhibitor
fluoxetine against the depression-related neurobehavioral ...
IV-Taller de Formulación y Gestión Académica de la Investigación
(2019-02-27)
La actividad pretendió abordar el tema de la obviedad que parece estar presente en muchas de las personas investigadoras, pero que a la hora de formular las propuestas eso que parece obvio no se incluye debilitando las ...
Clinical and Genetic Analysis of Costa Rican Patients With Parkinson's Disease
(2021)
Background: Most research in genomics of Parkinson’s disease (PD) has been done
in subjects of European ancestry, leading to sampling bias and leaving Latin American
populations underrepresented. We sought to clinically ...