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Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice
The local and systemic pathological changes induced by an i.m. injection of 100 micrograms of Bothrops asper venom in mice were studied histologically and by following the changes in serum levels of enzymes, proteins, ATP ...
Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice
The mode by which coral snake (Micrurus nigrocinctus) venom affects skeletal muscle was studied using a combined approach. The venom induced early functional and structural alterations in the plasma membrane of muscle ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...