Listar Salud por título
Mostrando ítems 1198-1217 de 4019
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Determinación indirecta, mediante marcadores de ADN, del estado de portadoras de distrofia muscular de Duchenne (DMD) en una familia costarricense
(Acta Pediátrica Costarricense 16 (1): 32-38, 2002)Estimar el riesgo de ser portadoras a mujeres emparentadas por línea materna con un paciente afectado con DMD. Sitio de realización: Instituto de Genética Humana, Universidad Friedrich Alexander Erlangen-Nuremberg e INISA, ... -
Determinación inmunoenzimática de los niveles séricos de inmunoglobina E en niños asmáticos de la Meseta Central de Costa Rica
(1991)Se describe los niveles de IgE sérica en una muestra de 69 niños con diagnóstico de asma bronquial, de la meseta central de Costa Rica, así como de 33 niños aparentemente sanos, sin historia clínica de alergias, y de 20 ... -
Determinantes de deterioro funcional acelerado en los pacientes con esclerosis lateral amiotrófica atendidos por primera vez en Centro Nacional de Control del Dolor y Cuidados Paliativos durante los años 2015 y 2016
(2020)Introducción: La esclerosis lateral amiotrófica es la enfermedad de las motoneuronas más frecuente; causa debilidad progresiva que genera limitación funcional acumulativa en el tiempo, llevando finalmente al fallecimiento. ... -
Determinantes de la calidad de vida relacionada con la salud oral en adultos mayores de un centro diurno costarricense: Resultados de un estudio piloto
(2021)El cambio de la distribución demográfica en Costa Rica establece a las personas adultas mayores (PAM) como una prioridad de salud pública. La salud oral es un indicador multidimensional, que incluye dimensiones biológicas, ... -
Determinantes del descenso de la mortalidad infantil en Costa Rica
(1985)En Costa Rica, la tasa de mortalidad infantil se ha reducido notablemente de 68 por 1 000 en 1970 a 20 por 1 000 en 1980. Con el propósito de identificar los posibles determinantes de esta reducción se analizaron los cambios ... -
Determinantes sociales de la salud y prevalencia de sobrepesoobesidad en mujeres urbanas, según nivel socioeconómico
(2021)La obesidad es un factor de riesgo para diferentes enfermedades crónicas y está asociada a factores genéticos, ambientales y sociales. Objetivo: analizar la asociación entre los determinantes sociales de la salud y ... -
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
(2019-11-08)The aim of this study is to determine the impact caused by direct compression on the crystalline state of two prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ... -
Developing a cooperative multicenter study in Latin America: Lessons learned from the Latin American Study of Nutrition and Health Project
(2017)This report examines the challenges of conducting a multicenter, cross-sectional study of coun- tries with diverse cultures, and shares the lessons learned. The Latin American Study of Nutrition and Health (ELANS) was used ... -
Development and distribution of cysts of an avirulent strain of Toxoplasma and the humoral immune response in mice
(1990)An avirulent T. gondii strain isolated from a owl (Glaucidium brasilúmum) produces randomIy distributed cysts in the brain of mice which can survive to inocula as high as lOOO oocysts. Cysts appeared for !he first time ... -
Development and validation of fluorescence live-cell imaging approaches to study flavivirus infection kinetics in animal cells
(2021-10-07)The genus Flavivirus in the family Flaviviridae comprises many clinically important viruses, such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus (YFV). The quest for therapeutic targets to combat ... -
Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom
(2016-09-15)A chicken-derived antivenom (ChDAv) towards taipan snake (Oxyuranus scutellatus) venom was produced by purifying anti-taipan IgY from egg yolks of hens immunized with taipan venom. The productivity, antivenomic profile, ... -
Development of an instrument-free and low-cost ELISA dot-blot test to detect antibodies against SARS-CoV-2
(2023-02)Most laboratory tests to detect the presence of anti-SARS-CoV-2 antibodies use ELISA or CLIA; however, equipment for these immunoassays is unavailable in many areas of low- and middle-income countries. Rapid lateral flow ... -
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
(2019)The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. Methods: According to a ... -
Development of immunoassays for determination of circulating venom antigens during envenomations by coral snakes (Micrurus species)
(1997-11)A reverse agglutination assay and two capture enzyme-linked immunoassays (ELISAs) for the quantitative determination of Micrurus nigrocinctus nigrocinctus venom antigens in fluids were developed using affinity-purified ... -
Development of nanobodies against hemorrhagic and myotoxic components of Bothrops atrox snake venom
(2020)Snake envenoming is a globally neglected public health problem. Antivenoms produced using animal hyperimmune plasma remain the standard therapy for snakebites. Although effective against systemic effects, conventional ... -
Development of novel microstructured lipid carriers for dissolution rate enhancement of albendazole
(2020-11-07)Objective: This study aimed to develop a microstructured lipid carrier that improves the rate of dissolution of the active pharmaceutical ingredient (API) Albendazole. Methods: A solvent diffusion method was used for the ... -
Diabetes epidemics: inequalities increase the burden on the healthcare system
(2019)Diabetes is a major cause of morbidity and mortality and represents a source of demands on already constrained healthcare systems in Latin America and the Caribbean. We estimate inequalities in diabetes incidence, prevalence ... -
Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
(Journal of Nervous and Mental Disease 2009;197: 530–535, 2009-07)We determined the rates of agreement between diagnoses, using the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived at, using additional sources of information, to establish whether there are differences ...