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Parasitismo imaginario: experiencia clínica y diagnóstica
(2012-06-01)Objetivo: describir los casos de parasitismo imaginario observados en el Laboratorio de Entomología Médica, Facultad de Microbiología, Universidad de Costa Rica durante 2001-2011. Métodos: se describen 9 casos cuyas ... -
Parálisis de plexo braquial obstétrico
(2023)La patología del plexo braquial obstétrico es una que ocurre con cierta frecuencia y que en el medio pasa desapercibida con inicios de control tardíos y con grandes repercusiones futu- ras para el paciente. Con el paso ... -
Parámetros técnicos óptimos para realizar una tomografía computarizada de alta resolución de tórax en pacientes adultos con enfermedad pulmonar intersticial difusa: revisión bibliográfica
(2023)El siguiente trabajo tiene como finalidad realizar una revisión bibliográfica acerca de la literatura de la tomografía computarizada de alta resolución de tórax, con la intensión de identificar los parámetros técnicos ... -
Parental age effects, but no evidence for an intrauterine effect in the transmission of myotonic dystrophy type 1
(European Journal of Human Genetics p.1-8, 2014-07-23)Myotonic dystrophy type 1 (DM1) is caused by the expansion of an unstable CTG repeat (g.17294_17296(45_1000)) with more repeats associated with increased disease severity and reduced age at onset. Expanded disease-associated ... -
Partial efficacy of a Brazilian coralsnake antivenom and Varespladib to neutralize distinct toxic effects induced by a sublethal Micrurus dumerilii carinicauda envenoming in rats
(2022)In this work, we reported the efficacy of a combination of Brazilian therapeutic coralsnake antivenom (CAV) and varespladib (phospholipase A2 inhibitor – VPL) in partially neutralizing selected toxic effects of Micrurus ... -
La participación comunitaria como recurso para la prevención del dengue en una comunidad urbana de San José, Costa Rica
(2005-06-01)Se implementó un modelo de participación comunitaria en dos de los cuatro sectores del caserío "La Carpio ",Distrito Uruca,San José, Costa Rica,el cual constituyó el primer poblado del Gran Área Metropolitana de San José ... -
Participatory risk mapping of malaria vector exposure in northern South America using environmental and population data
(2014-03-01)Malaria elimination remains a major public health challenge in many tropical regions, including large areas of northern South America. In this study, we present a new high spatial resolution (90 × 90 m) risk map for Colombia ... -
Pasado, presente y futuro de la citogenética en Costa Rica
(Revista de Biología Tropical 52 (3) 537-544, 2004)Esta es una breve descripcion de lo que ha sido el desarrollo de la citogenética humana en Costa Rica, la situacion actual y las expectativas a corto plazo. Esta ciencia- arte nacio hace poco más de cuarenta años en ... -
Paternidad y derechos sexuales: tendencias actuales sobre el ejercicio de la paternidad: una revisión integrativa
(2019)El presente trabajo tiene como objetivo indagar y describir las tendencias con respecto al ejercicio de la paternidad a partir de la evidencia científica que reseña la literatura, partiendo de los derechos sexuales y ... -
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
(2016-09-01)The pathogenesis of dermonecrosis induced by the venom of the African spitting cobra Naja nigricollis was investigated in a mouse model. Intradermal injection of venom induced a macroscopic necrotic lesion. Histological ... -
Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice
(1986-02)The mode by which coral snake (Micrurus nigrocinctus) venom affects skeletal muscle was studied using a combined approach. The venom induced early functional and structural alterations in the plasma membrane of muscle ... -
Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms
(2013-12-15)Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments, purified from the plasma of animals immunized with snake venoms. Their therapeutic success lies in their ability to mitigate the progress ... -
Pathogenic potential of a Costa Rican strain of ‘Candidatus Rickettsia amblyommii’ in guinea pigs (Cavia porcellus) and protective immunity against Rickettsia rickettsii
(2015-07)‘Candidatus Rickettsia amblyommii’ is a spotted fever group rickettsia that is not considered pathogenic, although there is serologic evidence of possible infection in animals and humans. The aim of this study was to ... -
Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom
(2001-06)The pathological alterations induced by neuwiedase, a 22 kDa class P-I metalloproteinase from the venom of the South American pit viper Bothrops neuwiedi, were studied in mice. Neuwiedase was devoid of hemorrhagic activity ... -
Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (Terciopelo)
(1992-09)Venom from newborn Bothrops asper snakes has higher lethal, hemorrhagic, edema-forming, proteolytic and defibrinating activities than venom from adult B. asper specimens. Electrophoretic analysis confirmed the variation ... -
Pathological changes induced by BaH1, a hemorrhagic proteinase isolated from Bothrops asper (Terciopelo) snake venom, on mouse capillary blood vessels
(1994-08)The pathological changes induced in capillaries by BaH1, a hemorrhagic metalloproteinase isolated from the venom of Bothrops asper, were studied after i.m. injection in mouse gastrocnemius. Hemorrhage was observed ... -
Pathology and first report of natural eye infection with the trematode Philophthalmus gralli (Digenea, Philophthalmidae) in Tinamus major (Tinamiformes, Tinamidae), Costa Rica
(2013)The eye-fluke Philophthalmus gralli (Philophthalmidae Looss, 1899) was found in six birds known as great tinamous (Tinamusmajor) reared in awild animal shelter located in Alajuela, Costa Rica. The birds presented conjunctival ... -
Patient Organizations’ Barriers in Pharmacovigilance and Strategies to Stimulate Their Participation
(2020)European drug regulations aim for a patient-centered approach, including involving patients in the pharmacovigilance (PV) systems. However many patient organizations have little experience on how they can participate in ... -
Patient Safety Indicators in Clinical Laboratories: An Exploratory Survey among Costa Rican Laboratory Professionals
(2021-02-13)Introduction: Patient safety indicators (PSIs) focus on the prevention of complications and minimization of unnecessary patient risk. Using the methodology known as SMART, the most suitable indicators may be selected by ...