Now showing items 1279-1298 of 2589

    • GABAergic modulation with classical benzodiazepines prevent stress-induced neuro-immune dysregulation and behavioral alterations 

      Ramírez Chan, Karol Gabriela; Niraula, Anzela; Sheridan, John F. (2016)
      Objective: Psychosocial stress is associated with altered immunity, anxiety, and depression. Repeated social defeat (RSD), a model of social stress, triggers egress of inflammatory myeloid progenitor cells (MPCs; ...
    • Gastrectomía Laparoscópica en Cáncer Gástrico 

      Jiménez Trigueros, José Pablo (2020)
      El adenocarcinoma gástrico es una de las neoplasias malignas más frecuentes, tanto en el ámbito mundial como en Costa Rica, además, presenta una de las morbimortalidades más elevadas en comparación con el resto de las ...
    • Gene admixture in the Costa Rican population 

      Morera Brenes, Bernal; Barrantes Mesén, Ramiro; Marín Rojas, Rafael (Ann Hum Genet; 67 (1) p. 71-80, 2003)
      The general population of Costa Rica has sometimes been considered to be the product of an amalgamation of groups of diverse origin. To determine the magnitude of accumulated admixture since Spanish colonization, 11 ...
    • Generational Transfers and Population Aging in Latin America 

      Rosero Bixby, Luis (Population and Development review 37 (Supplement): 143–157 (2011) 143, 2011)
      Population aging, a direct consequence of the demographic transition, is often portrayed in negative, even dire terms. This chapter examines some of the probable effects of population aging in Latin America within the ...
    • Genetic diversity and evolution of the human leptin locus tetranucleotide repeat 

      Moffett, Susan; Martinson, Jeremy; Shriver, Mark D.; McGarvey, Stephen T.; Ferrell, Robert E.; Barrantes Mesén, Ramiro (Hum Genet 110; p. 412-417, 2002)
      To better understand the evolutionary history of the gene region containing the multifunctional adipose tissue hormone leptin, we genotyped 1,957 individuals from 12 world populations for a highly variable tetranucleo ...
    • Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction 

      Cornelis, Marilyn C.; El-Sohemy, Ahmed; Campos Núñez, Hannia (2004)
      There is growing evidence that DNA damage caused by mutagens found in tobacco smoke may contribute to the development of coronary heart disease (CHD). In order to bind to DNA many mutagens require metabolic activation by ...
    • Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption 

      Cornelis, Marilyn C.; El-Sohemy, Ahmed; Campos Núñez, Hannia (2007)
      Background: Caffeine is the most widely consumed stimulant in the world, and individual differences in response to its stimulating effects may explain some of the variability in caffeine consumption within a population. ...
    • Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences 

      Silva de la Fuente, Sandra Maria; Escamilla, Michael; Ontiveros, Humberto; Mendoza Rodríguez, Ricardo; Muñoz, Rodrigo; Raventós Vorst, Henriette; Campos Sánchez, Rebeca; Barrantes Mesén, Ramiro (Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
      Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to ...
    • Genetic structure of personality factors and bipolar disorder in families segregating bipolar disorder 

      Hare, Elizabeth; Contreras Rojas, Javier; Flores, Deborah; Jerez, Álvaro; Nicolini Sánchez, José Humberto; Ontiveros Sánchez de la Barquera, Jose Alfonso; Almasy, Laura; Escamilla, Michael; Raventós Vorst, Henriette (Journal of Affective Disorders xxx (2011) xxx–xxx, 2011)
      Bipolar disorder (BPD) has been associated with variations in personality dimensions, but the nature of this relationship has been unclear. Inthis study, theheritabilities of BPDandtheBig Five personality factors and the ...
    • Genetic variants of the lipoprotein lipase gene and myocardial infarction in the Central Valley of Costa Rica 

      Yang, Yadong; Ruiz Narváez, Edward A.; Niu, Tianhua; Xu, Xiping; Campos Núñez, Hannia (2004)
      To assess common variants of the LPL gene that could influence susceptibility to myocardial infarction (MI), we assessed three functional single-nucleotide polymorphisms (SNPs), D9N, N291S, and S447X, in 1,321 survivors ...
    • Genetic variation and racial admixture in the Miskito of the southern Mosquito Shore, Nicaragua 

      Azofeifa Navas, Jorge; Ruiz Narváez, Edward A.; Barrantes Mesén, Ramiro (1998)
      A survey of the electrophoretic variation at eleven loci red-blood cell enzymes. hemoglobins and serum proteins was performed on a sample of 59 Miskitos stemming from the southernmost part of the Mosquito shore of Nicaragua. ...
    • Genetic variation at twentythree microsatellite loci in sixteen human populations 

      Deka, Ranjan; Shriver, Mark D.; Yu, Ling Mei; Mueller Heidreich, Elisa; Jin, Li; Zhong, Yixi; McGarvey, Stephen T.; Swarup Agarwal, Shyam; Bunker, Clareann H.; Miki, Tetsuro; Hundrieser, Joachim; Yin, Shih-Jiun; Raskin, Salmo; Barrantes Mesén, Ramiro; Ferrell, Robert E.; Chakraborty, Ranajit (1999-08)
      We have analysed genetic variation at 23 microsatellite loci in a global sample of 16 ethnically and geographically diverse human populations. On the basis of their ancestral heritage and geographic locations, the studied ...
    • Genetic variation in the Bribri and Cabecar Amerindians from Talamanca, Costa Rica 

      Azofeifa Navas, Jorge; Barrantes Mesén, Ramiro (1991)
      A screening of more than 40 loci was performed in the Bribri and Cabecar Amerindian populations of Talamanca in Southeastern Costa Rica. Some differences were found in the distribution (presence or absence) of the variants ...
    • Genetic variation of the Y chromosome in Chibcha-Speaking amerindians of Costa Rica and Panama 

      Ruiz Narváez, Edward A.; Santos, Fabricio R.; Carvalho Silva, Denise R.; Azofeifa Navas, Jorge; Barrantes Mesén, Ramiro; Peña, Sergio D. J. (Human Biology 77(1): 71-91, 2005)
      Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS 19, DYS389A, DYS389B, DYS390, DYS391, and ...
    • Genetic, dietary, and other lifestyle determinants of serum homocysteine levels in young adults in Costa Rica 

      Holst Schumacher, Ileana; Monge Rojas, Rafael; Cambronero Gutiérrez, Priscilla; Brenes Camacho, Gilbert (2005)
      Objective: Elevated serum total homocysteine (tHcy) is considered an independent risk factor for cardiovascular disease. The objective of this study was to develop the first-ever information on the prevalence of ...
    • Genética de la esquizofrenia: avances en el estudio de genes candidatos 

      Pacheco, Adriana; Raventós Vorst, Henriette (Rev. biol. trop v.52 n.3, p. 467-473 sep. 2004, 2004)
      Genetics of Schizophrenia: advances in the study of candidate genes. Schizophrenia is one of the most severe mental disorders that affect 1% of the population worldwide. It is clear that both genetic and environmental ...
    • La genética humana en Costa Rica situación actual y sus perspectivas 

      Barrantes Mesén, Ramiro (1985)
      Se analiza la situación de la genética humana en Costa Rica mediante un estudio de la literatura científica publicada entre 1964 y 1984. Se muestra que a partir de 1976 se ha incrementado el número de publicaciones en este ...
    • Genotoxicidad de tres plaguicidas utilizados en la actividad bananera de Costa Rica 

      Vindas Smith, Rebeca; Ortiz Morales, Fernando; Ramírez Mayorga, Vanessa; Cuenca Berger, Patricia (Revista de Biología Tropical 52(3) p.601-609, 2004-12-15)
      Se evaluó la genotoxicidad in vitro de los fungicidas imazalil y tiabendazol y del insecticida clorpirifos, formulaciones empleadas en las bananeras costarricenses, utilizando la técnica de electroforesis de células únicas ...
    • Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom 

      Vélez, Sara María; Salazar, Marcos H.; Acosta de Patiño, Hildaura; Gómez de González, Leandra Yolanda; Rodriguez, Abdiel; Correa, David; Saldaña, Julio; Navarro, Deyvi; Lomonte, Bruno; Otero Patiño, Rafael; Gutiérrez, José María (2017-06)
      Bothrops asper is the medically most important venomous snake in Central America. In Panama, the country having the highest incidence of snakebites in Latin America, B. asper is widely distributed throughout the country ...
    • Giardiasis: Impact on child growth 

      Farthing, Michael J. G.; Mata Jiménez, Leonardo; Urrutia, Juan José; Kronmal, Richard A. (1986)
      Chronic disorders of the gastrointestinal tract may impair physical growth during infancy and childhood. Growth retardation has been particularly well documented in children with Crohn's disease and coeliac disease in which ...