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El suero antiofídico polivalente producido en Costa Rica: Estabilidad y capacidad neutralizante
(1988)
En este trabajo se revisan y discuten una serie
de aspectos relativos a la producción,
estabilidad y capacidad neutralizante del suero
antiofídico polivalente producido por el Instituto
Clodomiro Picado. Este suero ...
South American snake venom proteins antigenically-related to Bothrops asper myotoxins.
(1990)
the presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using poluclonal and monoclonal antibodies. 2. Myotoxin-like components ...
Effects of a myotoxic phospholipase A2 isolated from Bothrops asper venom on skeletal muscle sarcoplasmic reticulum
(1987)
The myotoxin from B. asper snake venom inhibited Ca-ATPase activity of rabbit sarcoplasmic reticulum after incubation in vitro. Inhibition was non-competitive and albumin enhanced the effect of the toxin. Furthermore, B. ...
Quantitation by enzyme-immunoassay of antibodies against Bothrops myotoxins in four commercially-available antivenoms
(1991)
An enzyme-immunoassay (EIA) for the quantitation of antibodies against myotoxins present in the venoms of Bothrops asper (Costa Rica), B. atrox (Colombia) and B. moojeni (Brazil), was developed. This EIA was utilized for ...
Neutralization of coral snake Micrurus nigrocinctus venom by a monovalent antivenom
(1991)
The neutralizing ability of a monovalent anti-Micrurus nigrocinctus (coral snake) antivenom produced in Costa Rica was tested against the lethal, myotoxic and phospholipase A2 activities of homologous venom. In addition, ...
Immunoglobulin G and F(ab')2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom
(1997-11)
The ability of whole immunoglobulin G (IgG) and F(ab')2 polyvalent (Crotalinae) antivenoms to neutralize the hemorrhagic, edema-forming and myotoxic activities of Bothrops asper venom was studied. Both antivenoms were ...
Isolation of a galactose-binding lectin from the venom of the snake Bothrops godmani (Godmann's pit viper).
(1990)
A galactose-binding
lectin, isolated from the venom of B. gotlmani by affinity chromatography . is
an acidic protein (pI 4.9) with a subunit mol. wt of about 14,000, occurring
mostly as a disulfide-linked dimer of 28,000. ...
Neutralization of four Peruvian Bothrops sp. snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: preclinical assessment
(2005-06)
Envenomations after bites inflicted by snakes of the genus Bothrops constitute a public health hazard in Perú, and the intravenous administration of equine-derived antivenoms represents the only scientifically validated ...
Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America
(1996)
De nombreuses envenimations ophidiennes en Amérique centrale sont dues aux crotales (famille des Viperidae) parmi lesquels Bothrops asper est le principal responsable. Quelques accidents sont provoqués par les serpents ...
Effect of storage temperature on the stability of polyvalent antivenom produced in Costa Rica.
(1990)
The effect of storage temperature on the stability of the liquid polyvalent (crotaline) antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was studied during a twelve-month period. The following parameters ...