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Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage 

Voisin, Mathieu-Benoit; Rucavado Romero, Alexandra; Morazán, Diego; Macêdo, Jéssica Kele A.; Calvete Chornet, Juan José; Sanz, Libia; Nourshargh, Sussan; Gutiérrez, José María; Fox, Jay W.; Herrera Arias, Cristina; Escalante Muñoz, Teresa (2015-04-24)
Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane components in vivo, as well as by a ...

Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics 

Calvete Chornet, Juan José; Arias, Ana Silvia; Rodríguez, Yania; Quesada Bernat, Sarai; Sánchez Céspedes, Laura Vanessa; Chippaux, Jean Philippe; Pla Ferrer, Davinia; Gutiérrez, José María (2016-09-01)
Snakebite envenoming has a heavy burden in the public health in sub-Saharan Africa. The viperid species Echis ocellatus (carpet viper or saw-scaled viper) is the medically most important snake in the savannahs of western ...

Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa 

Calvete Chornet, Juan José; Cid, Pedro; Sanz, Libia; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Herrera Vega, María; León Montero, Guillermo; Harrison, Robert A.; Durfa, Nandul; Nasidi, Abdulsalami; Theakston, R. David G.; Warrell, David A.; Gutiérrez, José María (2010)
The immunoreactivity of EchiTAb-Plus-ICP, an antivenom developed for the treatment of snakebite envenoming in sub-Saharan Africa, to venoms of seven Echis and Bitis species, was assessed by “antivenomics.” This proteomic ...

Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil 

Jorge, Roberta Jeane B.; Monteiro, Helena S. A.; Gonçalves Machado, Larissa; Guarnieri, Míriam C.; Ximenes, Rafael M.; Borges Nojosa, Diva M.; de O. Luna, Karla P.; Zingali, Russolina B.; Corrêa Netto, Carlos; Gutiérrez, José María; Sanz, Libia; Calvete Chornet, Juan José; Pla Ferrer, Davinia (2015-01-30)
The Caatinga lancehead, Bothrops erythromelas, is a medically relevant species, responsible for most of the snakebite accidents in most parts of its distribution range in northeastern Brazil. The spectrum and geographic ...

Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus 

Angulo Ugalde, Yamileth; Castro Godínez, Adriana; Lomonte, Bruno; Rucavado Romero, Alexandra; Fernández Ulate, Julián; Calvete Chornet, Juan José; Gutiérrez, José María (2014-12)
Four disintegrins were isolated from the venoms of the Central American viperid snakes Atropoides mexicanus (atropoimin), Bothrops asper (bothrasperin), Cerrophidion sasai (sasaimin), and Crotalus simus (simusmin). ...

Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids 

Fernández Ulate, Julián; Vargas Vargas, Nancy; Pla Ferrer, Davinia; Sasa Marín, Mahmood; Rey Suárez, Paola; Sanz, Libia; Gutiérrez, José María; Calvete Chornet, Juan José; Lomonte, Bruno (2015-12-01)
Protein composition, toxicity, and neutralization of the venoms of Micrurus alleni and Micrurus mosquitensis, two sympatric monadal coral snakes found in humid environments of the Caribbean region of Costa Rica, were ...
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Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon 

Lomonte, Bruno; Tsai, Wan-Chih; Ureña Diaz, Juan M.; Sanz, Libia; Mora Obando, Diana; Sánchez, Elda; Fry, Bryan G.; Gutiérrez, José María; Gibbs, H. Lisle; Sovic, Michael G.; Calvete Chornet, Juan José (Journal of Proteomics vol 96, p.103-116, 2014-01-16)
Wereport a genus-wide comparison of venomproteomevariation acrossNewWorld pit vipers in the genus Agkistrodon. Despite the wide variety of habitats occupied by this genus and that all its taxa feed on diverse species of ...

Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii 

Fernández Ulate, Julián; Gutiérrez, José María; Calvete Chornet, Juan José; Sanz, Libia; Lomonte, Bruno (2016-06)
Snake venoms are composed mainly of a mixture of proteins and peptides. Notably, all snake venom toxins have been assigned to a small number of protein families. Proteomic studies on snake venoms have recently identified ...

Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa 

Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Herrera Vega, María; León Montero, Guillermo; Harrison, Robert A.; Durfa, Nandul; Nasidi, Abdulsalami; Calvete Chornet, Juan José; Theakston, R. David G.; Warrell, David A.; Gutiérrez, José María (2010-02)
A preclinical assessment was performed on the neutralizing efficacy of a whole IgG polyspecific antivenom (EchiTAb-Plus-ICP®), designed for the treatment of snakebite envenomings in Nigeria. It was generated by immunizing ...

Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria 

Sánchez Céspedes, Laura Vanessa; Pla Ferrer, Davinia; Herrera Vega, María; Chippaux, Jean Philippe; Calvete Chornet, Juan José; Gutiérrez, José María (2015-11)
Snakebite envenoming causes a heavy toll in sub-Saharan Africa in terms of mortality and sequelae. In the West African savannah, the viperid Echis ocellatus is responsible for the vast majority of bites. In the last decades, ...
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Calvete Chornet, Juan José (67)
Gutiérrez, José María (57)Sanz, Libia (47)Lomonte, Bruno (43)Angulo Ugalde, Yamileth (23)Pla Ferrer, Davinia (21)Fernández Ulate, Julián (16)Herrera Vega, María (9)León Montero, Guillermo (9)Sasa Marín, Mahmood (9)... View MoreTypeinfo:eu-repo/semantics/article (64)Artículo científico (62)Capítulo de libro (1)Contribución a publicación periódica (1)info:eu-repo/semantics/bookPart (1)info:eu-repo/semantics/contributionToPeriodical (1)info:eu-repo/semantics/preprint (1)Preprint (1)ProcedenceVicerrectoría de Investigación (67)Vicerrectoría de Docencia (5)... View MoreHas File(s)Yes (67)

  • Repositorios universitarios

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Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica