Universidad de Costa Rica
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo Depositar
  • Políticas
  • Contacto
    • español
    • English
  • English 
    • español
    • English
  • Login
Search 
  •   Kérwá Home
  • Investigación
  • Salud
  • Search
  •   Kérwá Home
  • Investigación
  • Salud
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-10 of 386

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100

DNase activity in Costa Rican crotaline snake venoms: quantification of activity and identification of electrophoretic variants. 

Sittenfeld Appel, Ana; Raventós Vorst, Henriette; Cruz, R.; Gutiérrez, José María (1991)
DNase activity of Costa Rican crotaline snake venoms from the genera Bothrops, Crotalus and Lachesis was quantified by an enzymodiffusion method on agarose/DNA gels containing ethidium bromide. The reaction is detected as ...

Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom 

Soares, Andreimar Martins; Andrião Escarso, Silvia H.; Bortoleto, Raquel K.; Rodrigues Simioni, Lea; Arni, Raghuvir K.; Ward, Richard John; Gutiérrez, José María; Giglio, José Roberto (2001-03-15)
Piratoxins (PrTX) I and III are phospholipases A2 (PLA2s) or PLA2 homologue myotoxins isolated from Bothrops pirajai snake venom, which also induce myonecrosis, bactericidal activity against Escherichia coli, disruption ...

Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants 

Chacur, Marucia; Longo, I.; Picolo, Gisele; Gutiérrez, José María; Lomonte, Bruno; Guerra, J. L.; Teixeira, Catarina de Fátima; Cury, Yara (2003-05)
The ability of Lys49 and Asp49 phospholipases A2 (PLA2), from Bothrops asper snake venom, to cause hyperalgesia was investigated in rats, using the paw pressure test. Intraplantar injection of both toxins (5–20 μg/paw) ...

Biological and biochemical activities of Vipera berus (European viper) venom 

Calderón Fuentes, Leonel; Lomonte, Bruno; Gutiérrez, José María; Tarkowski, Andrej; Hanson, Lars Ake (1993-06)
Vipera berus is widely distributed throughout the northern part of Europe and Asia. Characterization of several toxic effects of its venom in the mouse, as well as of in vitro enzymatic activities was performed. Vipera ...
Thumbnail

Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows 

Estrada Umaña, Ricardo; Herrera Vega, María; Segura Ruiz, Álvaro; Araya, Javier; Boschini Figueroa, Carlos; Gutiérrez, José María; León Montero, Guillermo (2010-11)
Administration of antivenoms to treat snakebite envenomings has the potential risk of inducing early adverse reactions. The mechanisms involved in these reactions are unclear. In this study, polyspecific antivenom consisting ...

Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica 

Laines, Johana; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Herrera Vega, María; Vargas Arroyo, Mariángela; Alvarez, Gladys; Gutiérrez, José María; León Montero, Guillermo (2014-09-15)
The toxicological profile of the venoms of the snakes Bothrops asper and Bothrops atrox from Ecuador was investigated, together with the venom of a population of B. asper formerly classified as ‘Bothrops xanthogrammus’. ...

Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test 

Herrera Vega, María; Tattini Jr., Virgilio; Pitombo, Ronaldo N. M.; Gutiérrez, José María; Borgognoni, Camila; Vega Baudrit, José; Solera, Federico; Cerdas Solís, Maykel; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Villalta Arrieta, Mauren; Vargas Arroyo, Mariángela; León Montero, Guillermo (2014-11)
Freeze-drying is used to improve the long term stability of pharmaceutical proteins. Sugars and polyols have been successfully used in the stabilization of proteins. However, their use in the development of freeze-dried ...
Thumbnail

Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities 

Antúnez Oliva, José; Fernández Ulate, Julián; Lomonte, Bruno; Angulo Ugalde, Yamileth; Sanz, Libia; Pérez, Alicia; Calvete Chornet, Juan José; Gutiérrez, José María (2010-09-30)
Viperid snakes of the genus Atropoides are distributed in Mexico and Central America and, owing to their size and venom yield, are capable of provoking severe envenomings in humans. This study evaluated, using an ‘antivenomics’ ...

Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms 

Segura Ruiz, Álvaro; Castillo, M. C.; Núñez Rangel, Vitelbina; Yarlequé, A.; Gonçalves, Luís Roberto de Camargo; Villalta Arrieta, Mauren; Bonilla, César; Herrera Vega, María; Fernández, M.; Yano, M. Y.; Araújo, H. P.; Boller, M. A. A.; León, P.; Tintaya, B.; Sano Martins, I. S.; Gómez, A.; Fernández, Gil Patrick; Geoghegan, Patricia; Higashi, Hisako Gondo; León Montero, Guillermo; Gutiérrez, José María (2010-11)
Species of the genus Bothrops induce the vast majority of snakebite envenomings in Latin America. A preclinical study was performed in the context of a regional network of public laboratories involved in the production, ...

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom 

Solano Trejos, María Gabriela; Segura Ruiz, Álvaro; Herrera Vega, María; Gómez Argüello, Aarón; Villalta Arrieta, Mauren; Gutiérrez, José María; León Montero, Guillermo (2010-09)
The lethality neutralization assay performed in mice is the standard recommended by the World Health Organization to estimate antivenom potency. The interpretation of its results without considering its analytical capacity ...
  • 1
  • 2
  • 3
  • 4
  • . . .
  • 39

  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
  • Biblioteca Digital del CIICLA
  • Repositorio Documental Rafael Obregón Loría (CIHAC)
  • Biblioteca Digital Carlos Melendez (CIHAC)
  • Repositorio de Fotografías
  • Colección de videos de UPA-VAS
  • Sitios recomendados

  • Buscador regional de LA Referencia
  • Buscador del Open ROAR
  • Scientific Electronic Library Online (SciELO)
  • Directory of Open Access Journals (DOAJ)
  • Redalyc
  • Redes sociales

  • facebook.com/repositoriokerwa
  • @Ciencia_UCR
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo depositar
  • Políticas
Contact Us | Send Feedback
Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica
 

 

Browse

All of KérwáCommunities & CollectionsTitlesAuthorsSubjectsProcedenceTypeThis CommunityTitlesAuthorsSubjectsProcedenceType

My Account

LoginRegister

Discover

Author
Gutiérrez, José María (386)
Lomonte, Bruno (170)Rucavado, Alexandra (62)Calvete Chornet, Juan José (55)León Montero, Guillermo (52)Angulo Ugalde, Yamileth (46)Sanz, Libia (41)Herrera Vega, María (35)Rojas Céspedes, Gustavo (33)Escalante Muñoz, Teresa (32)... View MoreType
info:eu-repo/semantics/article (386)
Artículo científico (377)info:eu-repo/semantics/publishedVersion (2)ProcedenceVicerrectoría de Investigación (385)Vicerrectoría de Docencia (25)... View MoreHas File(s)Yes (386)

  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
  • Biblioteca Digital del CIICLA
  • Repositorio Documental Rafael Obregón Loría (CIHAC)
  • Biblioteca Digital Carlos Melendez (CIHAC)
  • Repositorio de Fotografías
  • Colección de videos de UPA-VAS
  • Sitios recomendados

  • Buscador regional de LA Referencia
  • Buscador del Open ROAR
  • Scientific Electronic Library Online (SciELO)
  • Directory of Open Access Journals (DOAJ)
  • Redalyc
  • Redes sociales

  • facebook.com/repositoriokerwa
  • @Ciencia_UCR
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo depositar
  • Políticas
Contact Us | Send Feedback
Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica