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Interactions of malnutrition and infection
(Arab World Printing House. In: Practical approaches to combat malnutrition with special reference to mothers and children. Cairo, Egypt. May 25-29, 1977. N.S. Scrimshaw y M. Gabr (editors). Ministry of Health, Cairo, Egypt, Arab World Printing House, Egypt, p.134-144, 1979., 1979-05)
It is impossible and impracticable to separate health problems from their environmental causes. Thus, a quick glance at the present world distribution of famine and of severe and chronic malnutrition reveals a concentration ...
Resultados de la categorización de una muestra de pacientes con diagnóstico de egreso de esquizofrenia
(Acta Médica Costarricense, abril-junio 2002, vol 44 (2), 2002-04)
La esquizofrenia es una enfermedad que afecta aproximadamente al 1% de la población mundial. Es
una de las enfermedades psiquiátricas más debilitantes con un alto costo económico, social, familiar y personal.
En Costa ...
Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases
(2011-12-08)
Hemorrhage is a clinically important manifestation of viperid snakebite envenomings, and is induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic SVMPs hydrolyze some basement membrane (BM) and ...
Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka
(2014-10-14)
The venom arsenal of the New Guinea small-eyed snake, Micropechis ikaheka, was investigated by a joint cDNA sequencing and venomics approach. Twenty-seven full-length DNA sequences encoding novel venom proteins were recovered ...
Turbidity of hyperimmune equine antivenom: the role of phenol and serum lipoproteins
(1993)
Twenty batches of polyvalent antivenom produced at the Instituto Clodomiro Picado were analyzed for turbidity, both before and after freezing-thawing and lyophilization. Eight batches became turbid upon freezing-thawing, ...
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing
(BMC Genomics, 12:259, 2011, 2011)
Background: A long term research goal of venomics, of applied importance for improving current antivenom
therapy, but also for drug discovery, is to understand the pharmacological potential of venoms. Individually ...
Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins
(PLoS Negl Trop Dis 6(2): e1526, 2012-02-21)
Skeletal muscle necrosis is a common manifestation of viperid snakebite envenomations. Venoms from snakes of the genus Bothrops, such as that of B. asper, induce muscle tissue damage at the site of venom injection, provoking ...
The Global Snake Bite Initiative: an antidote for snake bite
(2010-01-02)
Clinicians have for a long time witnessed the tragedy of
injury, disability, and death from snake bite that is a daily
occurrence in many parts of Africa, Asia, and Latin
America. To many people living in these ...
Elapid venom toxins: multiple recruitments of ancient scaffolds
(1999-01)
Nigroxins A and B, two myotoxic phospholipases A2 (PLA2s) from the venom of the American elapid Micrurus nigrocinctus, belong to a new PLA2 subclass. Their primary structures were established and compared with those of ...
Horse IgG isotypes and cross-neutralization of two snake antivenoms produced in Brazil and Costa Rica
(2000-05)
Horse IgG isotypes and cross-neutralization of two snake antivenoms produced in Brazil and Costa Rica. Toxicon 000–000. This work compared the specificity, ELISA titers and IgG subclass content of the polyvalent antivenom ...