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Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights
(2012-02-16)
Within the Neotropical pit vipers, a lineage of primarily Middle American snake species
referred to as the “Porthidium group” includes the genera Atropoides, Cerrophidion, and
Porthidium. In this study, the venom proteomes ...
Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica
(2012-04)
The genus Bothriechis comprises a lineage of nine species of Neotropical pitvipers distributed mainly in highlands across Middle America, all adapted to arboreal habitats. Bothriechis supraciliaris is a relatively recently ...
The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study
(1994-01)
The acute tissue damaging effects of Bothrops riper snake
venom and a myotoxic Lys-49 phospholipase A2 (myotoxin In on the mouse
cremaster muscle were studied by intravital and electron microscopy. Both
venom and myotoxin ...
Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops Asper.
(1992)
In order to investigate the distribution of myotoxin isoforms in the snake Bothrops asper,
venoms from individual specimens were analyzed by a cathodic electrophoretic system for basic proteins
under native conditions.The ...
South American snake venom proteins antigenically-related to Bothrops asper myotoxins.
(1990)
the presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using poluclonal and monoclonal antibodies. 2. Myotoxin-like components ...
Immunoenzymatic quantitation of antibodies to Bothrops asper myotoxins after polyvalent antivenom administration in mice.
(1992)
Two quantitative enzyme-immunoassays (EIA) for Bothrops asper myotoxin and anti-myotoxin antibodies, respectively, were utilized to study their in vivo distribution in mice (Swiss, 18 to 20 g). 2. After polyvalent antivenom ...
Effect of storage temperature on the stability of polyvalent antivenom produced in Costa Rica.
(1990)
The effect of storage temperature on the stability of the liquid polyvalent (crotaline) antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was studied during a twelve-month period. The following parameters ...
Acute-phase reactions, including cytokines, in patients bitten by Bothrops and Crotalus snakes in Brazil
(1995)
Thirty-one patients bitten by venomous snakes in Botucatu area (State of São
Paulo - Brazil), sixteen by Bothrops spp. and fifteen by Crotalus durissus terrificus, were
studied. The group comprised twenty-nine males and ...
Neutralization of myonecrosis, hemorrhage, and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice
(1996)
The ability of pre-existing antibodies to neutralize locally-acting toxins of Bothrops
asper snake venom was investigated. Hemorrhage, myonecrosis, and edema
were markedly reduced in actively immunized mice, although ...
Similar effectiveness of Fab and F(ab')2 antivenoms in the neutralization of hemorrhagic activity of Vipera berus snake venom in mice
(1996)
The ability of two antivenoms to Vipera spp., consisting of Fab (Therapeutic Antibodies), or of F(ab′)2 (Zagreb Institute of Immunology) antibody fragments, to neutralize the hemorrhagic activity of Vipera berus snake venom ...