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Now showing items 271-280 of 282
Las citokinas, elementos centrales para la comprensión y manipulación terapéutica del sistema inmune (Parte II)
(1996)
Las citokinas están interrelacionadas en una red funcional, la cual está finamente regulada. El balance en la producción de estas proteínas va a jugar un papel determinante en dirigir al sistema inmune hacia un determinado ...
Las citokinas, elementos centrales para la comprensión y manipulación terapéutica del sistema inmune (Parte 1)
(1995)
Dentro del explosivo desarrollo en que se encuentra la inmunología básica, el campo de las citokinas y sus funciones dentro (y fuera) del sistema inmune, es uno de los que crece más vertiginosamente. En la primera parte ...
Phospholipase A2 and inflammation
Pathobiological activities of human group II phospholipase A2 in inflammation: do they all depend on its enzymatic action?
(1995)
Increased expression of secreted group II phospholipase A 2 (sPLA2) is associated with inflammation 1.This enzyme can promote a variety of potentially harmful events, which have been attributed to its catalytic activity. ...
Isolation of a galactose-binding lectin from the venom of the snake Bothrops godmani (Godmann's pit viper).
(1990)
A galactose-binding
lectin, isolated from the venom of B. gotlmani by affinity chromatography . is
an acidic protein (pI 4.9) with a subunit mol. wt of about 14,000, occurring
mostly as a disulfide-linked dimer of 28,000. ...
Patogénesis y neutralización de los efectos locales inducidos por el veneno de la serpiente "terciopelo" (Bothrops asper).
(1982)
Se presenta la revisión de varias investigaciones sobre la patogénesis y neutralización de los efectos locales inducidos por el veneno de la serpiente terciopelo. El cuadro local está constituido por mionecrosis, hemorragia ...
Medicinal plants with inhibitory properties against snake venoms
(2005)
Envenomations due to snake bites are commonly treated by parenteral administration of horse or
sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, despite the widespread
success of this ...
Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle
(2005)
Phospholipases A2 (PLA2) are important constituents of snake venoms, being responsible for several of their toxic actions.
Extracts from plants used in folk medicine were screened for inhibition of the enzymatic activity ...
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region
(2005)
A short peptide derived from the C-terminal region of Bothrops asper myotoxin II, a Lys49 phospholipase A2 (PLA2), was
previously found to reproduce the bactericidal activity of its parent molecule. In this study, a panel ...
Structure of myotoxin-II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom
(2006)
Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic
proteins which, although lacking catalytic activity, possess the ability to disrupt
biological membranes, inducing significant muscle-tissue loss ...
Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model
(2010)
Bee stings are a health concern in the Americas, where fatal envenomings due to massive
attacks by Africanized honeybees have been documented in the last decades. Most studies
on the toxic effects of honeybee venom in ...