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Dengue Virus Infection of Primary Human Smooth Muscle Cells
(2018-11-05)
Dengue virus (DENV) infection of humans is presently the most important arthropod-borne viral global threat, for which no suitable or reliable animal model exists. Reports addressing the effect of DENV on vascular components ...
Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms
(2018-06)
Snakebite envenoming by viperid species, and by some elapids, is characterized by a complex pattern of
tissue damage at the anatomical site of venom injection. In severe cases, tissue destruction may be so
extensive as ...
Emergence of an Outbreak-Associated Clostridium difficile Variant with Increased Virulence
(2015-04)
The prevalence of Clostridium difficile infections has increased due to the emergence of epidemic variants from diverse genetic lineages. Here we describe the emergence of a novel variant during an outbreak in a Costa Rican ...
Social gradient in cancer incidence in Costa Rica: Findings from a national population-based cancer registry
(2020)
Background: The main evidence regarding social inequalities in cancer risk comes from industrialized countries. The aim of this manuscript was to analyze the association between cancer incidence and socioeconomic position ...
Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models
(2020)
The Duvernoy's gland secretory proteome of the false coral snake Rhinobothryum bovallii (Costa Rica), unveiled applying bottom-up venomics, comprises a handful of toxins belonging to only three protein families, three-finger ...
Regional warming and the thermal regimes of American crocodile nests in the Tempisque Basin, Costa Rica
(2016-06-11)
Spatial variation in global climate change makes population-specific responses to this enigmatic threat pertinent on a regional scale. Organisms with temperature-dependent sex determination (TSD) potentially possess a ...
Degradation of naproxen and carbamazepine in spiked sludge by slurry and solid-phase Trametes versicolor systems
(2010-04)
rowth and activity of the white-rot fungus Trametes versicolor on sewage sludge were assessed in bio slurry and solid-phase systems. Bioslurry cultures with different loads of sludge (10%, 25% and 38%, w/v)
were performed. ...
Crystallographic and Topographic Analysis of Ultra-Translucent Zirconia After Various Surface Treatments
Análisis cristalográfico y topográfico de la zirconia ultra-translúcida después de diversos tratamientos de superficie
(2024-03-07)
The aim of the present study was to analyze the effects of 4 different surface treatments, on the crystallographic characteristics of Ultra-Translucent Zirconia. Fully sintered zirconia specimens of highly translucent ...
Isolation and molecular characterization of Acanthamoeba and Balamuthia mandrillaris from combination shower units in Costa Rica
(2014-08-19)
Free living amoebae (FLA) are ubiquitous protozoa, which may behave as parasites under certain conditions. Four genera are recognized as causal agents of infections in humans and animals: Naegleria, Sappinia, Acanthamoeba ...
SARS-CoV-2 genomic surveillance in Costa Rica: Evidence of a divergent population and an increased detection of a spike T1117I mutation
(2021)
Genome sequencing is a key strategy in the surveillance of SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Latin America is the hardest-hit region of the world, accumulating almost 20% of COVID-19 cases ...