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Detection of an undescribed Rickettsia sp. in Ixodes boliviensis from Costa Rica
(2014)
Ixodes boliviensis is a tick of carnivores that is common on domestic dogs. The only Rickettsia that has been detected previously in this species is 'Candidatus Rickettsia andeanae'. We report the detection of an undescribed ...
Especialidades médico forenses de la Universidad de Costa Rica: fortalezas y desafíos
Medical forensic specialties of the University of Costa Rica: Strengths and Challenges
(2021-01)
El Programa de Posgrado en Especialidades Médico Forenses de la Universidad de Costa Rica,
presenta una serie de particularidades propias que le confieren fortalezas, tales como el
convenio interinstitucional con el Poder ...
Pros and cons of different therapeutic antibody formats for recombinant antivenom development
(2018-05)
Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by the many
advances in immunology, synthetic biology, and antibody research, different approaches and antibody
formats are being ...
Evaluation of the critical points in the validation of 500 mg levofloxacin tablets for dissolution profile
(2016)
The method was validated by ultraviolet spectrophotometry for the
determination of levofloxacin 500 mg tablets using dissolution profiles
to establish therapeutic equivalence. The parameters were satisfactory
according ...
High Efficacy of Therapeutic Equine Hyperimmune Antibodies Against SARS-CoV-2 Variants of Concern
(2021)
SARS-CoV-2 variants of concern show reduced neutralization by vaccine-induced and
therapeutic monoclonal antibodies; therefore, treatment alternatives are needed. We
tested therapeutic equine polyclonal antibodies (pAbs) ...
Community Private Pharmacy in Costa Rica
(2018)
The private sector is composed of a wide range of services, with different levels of complexity, from ambulatory to hospital care. These services are financed through private insurances and out of pocket (5). Community ...
Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo
(2022-06)
Abstract: Extracellular vesicles (EVs) are small lipid vesicles released by both prokaryotic and eu-karyotic cells, involved in intercellular communication, immunomodulation and pathogenesis. In this study, we performed a ...
Extracellular vesicles of Trypanosoma cruzi and immune complexes they form with sialylated and non-sialylated IgGs increase small peritoneal macrophage subpopulation and elicit different cytokines profiles
(2023)
American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite Trypanosoma cruzi and is characterized by the presence of cardiac or gastrointestinal symptoms in a large number of patients during the chronic ...
Ultrastructural alterations in mouse capillary blood vessels after experimental injection of venom from the snake Bothrops asper (Terciopelo)
(1992-10)
Histological and ultrastructural alterations in capillary blood vessels were studied at various time intervals after im injection of 50 micrograms of Bothrops asper snake venom in mouse gastrocnemius muscle. Hemorrhage was ...
Análisis de la mortalidad de la Sección Medicina del Hospital Rafael Angel Calderón Guardia del 2001 al 2003
(Revista Médica de Costa Rica y Centroamérica LXI(568):105-111, 2004)
El objetivo de este estudio fue describir los patrones de mortalidad de la sección de medicina del Hospital Calderón Guardia y compararla con la mortalidad general y la publicada en la literatura mundial. Hubo 895 ...