Now showing items 1-10 of 2117
El uso de animales de experimentación en la investigación biomédica en Costa Rica
Using Experimental Animal in Biomedical Research in Costa Rica
(Acta Médica Costarricense 52(3), 2010-07)
El progreso en la investigación médica y biológica ha dependido en gran medida del uso de animales experimentales Dada la importancia que históricamente han tenido los animales como reactivos biológicos en la investigación ...
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite the outbreaks ...
Immunohistochemical demonstration of the binding of bothrops asper myotoxin to skeletal muscle sarcolemma
The binding of Bothrops asper myotoxin to mouse skeletal muscle was studied at both the light and electron microscope levels using the peroxidase anti-peroxidase technique. The toxin binds to muscle cell sarcolemma, and ...
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
Envenomations by Bothrops asper are often associated with complex and severe local pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and hemorrhage. The pathogenesis of these alterations ...
Rehidratación post-ejercicio: bebidas con alto contenido de potasio vs. agua y una bebida deportiva
Post-exercise Rehydration: potassium-rich drinks vs. water and a sports drink
RESUMEN Propósito: evaluar la efectividad, tolerancia y aceptación de dos bebidas ricas en potasio, comparadas con una bebida deportiva y agua, durante la rehidratación post-ejercicio. Metodología: en cuatro días diferentes, ...
Voluntary Fluid Intake with Milk or Chocolate Milk in Boys Exercising in the Heat
The main goal of this study was to compare fluid balance (FB) and voluntary intake (VI) in 10-to 14-year-old boys, when they combine partially skimmed milk or chocolate milk with water during exercise in the heat, as an ...
Arboviral encephalitis in Costa Rican horses: 2009-2016
Arbovirus of the genus Alphavirus and Flavivirus can cause febrile illness and sometimes neurological disease in both humans and animals. West Nile Virus (WNV), Eastern Equine Encephalitis Virus (EEEV), Western Equine ...
The evolution of diarrhoeal diseases and malnutrition in Costa Rica: The role of interventions
(Assignment Child (61-62) p.195-224, 1983)
Costa Rica has an infant mortality rate of 17.7%, one of the lowest for developing countries. While it is noted that it is difficult to demonstrate the contributions of specific interventions in accounting for the drastic ...