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High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees
(American Journal of Physical Anthropology 2012 July ; 148(3): 327–333., 2012-07)
Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial
DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming
that molecular evolution is clock-like) ...
Mitochondrial polymorphisms are associated both with increased and decreased longevity
(Hum Hered 2009;67:147–153, 2008-12-15)
Previous work compared frequency of longevity-associated polymorphisms (LAPS) in long-lived individuals and in controls from the general population (primarily in Europe and Japan), suggesting the polymorphisms are responsible ...
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
(Human Biology Open Access Pre-Prints. Paper 34., 2013-10-09)
Study for the first time a random sample from all regions of the country with AIMS (Ancestry Informative Markers) to address the individual and regional admixture proportions. A sample of 160 male individuals was screened ...
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
(Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico,
and the Hispanic population of the southwestern United States were
studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA
were analyzed to ...