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dc.creatorSantos Pasamontes, María
dc.creatorWard, R. H.
dc.creatorBarrantes Mesén, Ramiro
dc.date.accessioned2015-08-03T17:55:01Z
dc.date.available2015-08-03T17:55:01Z
dc.date.issued1994
dc.identifier.citationhttp://www.jstor.org/stable/pdf/41465033.pdf?acceptTC=truees_ES
dc.identifier.issn0018-7143
dc.identifier.issn1534-6617
dc.identifier.urihttp://hdl.handle.net/10669/15163
dc.descriptionArtículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 1994es_ES
dc.description.abstractThe genetic variation in a Chibcha-speaking Amerindian tribe from lower Central America, the Huetar, was analyzed using nucleotide sequences of the hypervariable segments of the mitochondria! DNA (mtDNA) control region, the frequencies of 10 Amerindian-specific mtDNA haplotypes, and the regional distribution of private protein polymorphisms. The sequencing of 713 base pairs (bp) in the control regions of 27 individuals revealed 11 distinct lineages. These were defined by 24 variable sites and a 6-bp deletion between nucleotide pairs (np) 106 and 111. The 6-bp deletion is a new mtDNA marker that will be valuable for Amerindian taxonomic research. Control region sequences and mtDNA haplotype analyses reveal that Huetar nitDNAs are distributed in 'Amerindian clusters" A, B, and D. A maximum-hlrellhood phylogenetic tree suggests a single origin for the 6-bp Huetar deletion in the sample. mtDNA haplotype analysis and the presence of previously characterized private protein variants (PEPA*F, TF*DCHI, and the absence of DI*A) show that the Huetar harbor polymorphisms of considerable antiquity, suggesting an early divergence from the regional founder gene pool for this population. The data also reflect a drastic constriction in population size. an evolutionary event with a proposed central effect on Huetar genetic structure.es_ES
dc.description.sponsorshipUniversidad de Costa Rica, Instituto de Investigaciones en Saludes_ES
dc.language.isoen_USes_ES
dc.sourceHuman Biology 66 (6): 963-977es_ES
dc.subjectmitochondrial DNAes_ES
dc.subjectHuman geneticses_ES
dc.subjectPoblación indígenaes_ES
dc.titlemtDNA variation in the chibcha ameridian huetar from Costa Ricaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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