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dc.creatorThompson, Elizabeth A.
dc.creatorNeel, James V.
dc.creatorSmouse, Peter E.
dc.creatorBarrantes Mesén, Ramiro
dc.date.accessioned2015-08-17T20:30:53Z
dc.date.available2015-08-17T20:30:53Z
dc.date.issued1992
dc.identifier.citationhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1682703/es_ES
dc.identifier.issn0002-9297
dc.identifier.urihttp://hdl.handle.net/10669/15230
dc.descriptionArtículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 1992. Este documento es privado debido a limitaciones de derechos de autor.es_ES
dc.description.abstractModels are developed for the survival, history, and spread of variant alleles, in order to consider what can, and what cannot, be inferred from this type of data. The high variances of the processes involved, and questions of sampling, place severe limitations on inferences. Nonetheless, by combining information on a number of rare variants observed in a group of interrelated populations, reliable qualitative inferences are possible. These ideas and models are developed in the context of data on five rare variants and six private polymorphisms observed in eight Chibcha-speaking tribes of Costa Rica and Panama. The decline and fragmentation of the Amerindian populations of Central America over the last 300 years create considerable difficulties in attempting inference of past genetic events. However, these tribes have been well studied genetically, anthropologically, and linguistically and thus provide an excellent framework for the study of rare-variant spread.es_ES
dc.description.sponsorshipUniversidad de Costa Rica, Instituto de Investigaciones en Saludes_ES
dc.language.isoen_USes_ES
dc.sourceThe American Journal Human Genetics 51(3): 609-626es_ES
dc.subjectCosta Ricaes_ES
dc.subjectgenes_ES
dc.subjectPanamaes_ES
dc.subjectamerindian populationses_ES
dc.subjectCentral Americaes_ES
dc.subjectgenetic eventses_ES
dc.subjectHuman geneticses_ES
dc.titleMicroevolution of the Chibcha-speaking peoples of Lower Central America: rare genes in an Amerindian complexes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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