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dc.creatorIrwin, Kathleen L.
dc.creatorRosero Bixby, Luis
dc.creatorOberle, Mark W.
dc.creatorLee, Nancy C.
dc.creatorWhatley, Anne S.
dc.creatorFortney, Judith A.
dc.creatorBonhomme, Michele G.
dc.date.accessioned2016-02-09T22:29:43Z
dc.date.available2016-02-09T22:29:43Z
dc.date.issued1988-01
dc.identifier.citationhttp://www.roserobixby.com/RoseroBixby/Publicaciones_files/101.pdf
dc.identifier.citationhttp://jama.jamanetwork.com/article.aspx?articleid=370061es_ES
dc.identifier.issn1538-3598
dc.identifier.urihttp://hdl.handle.net/10669/15569
dc.descriptionArtículo científico -- Universidad de Costa Rica. Instituto de Investigaciones en Salud, 1988es_ES
dc.description.abstractTo examine the relationship between cervical cancer and oral contraceptive (OC) use, we analyzed data from a population-based, case-control study in Costa Rica. Women aged 25 to 58 years in whom cervical cancer was diagnosed and reported to the National Tumor Registry were examined as two separate case groups: invasive cervical cancer and carcinoma in situ (CIS). Controls were women aged 25 to 58 years identified through a national survey. Women who had used OCs had no increased risk of invasive cervical cancer compared with women who had never used OCs (relative risk, 0.8; 95% confidence interval, 0.5 to 1.3). Women who had used OCs had an increased risk of CIS compared with those who had never used OCs (relative risk, 1.6; 95% confidence interval, 1.2 to 2.2). However, further analyses indicated that this increased risk was confined to those who had recently used OCs. Also, the risk of CIS was not elevated in subgroups in which a history of cervical smears was not strongly linked to OC use. The elevated risk of CIS among (DC users may therefore reflect a bias caused by enhanced detection of disease rather than a causal association.es_ES
dc.description.sponsorshipUniversidad de Costa Rica. Instituto de Investigaciones en Salud.es_ES
dc.language.isoen_USes_ES
dc.sourceJournal of the American Medical Association 259 (1): 59-64es_ES
dc.subjectCosta Ricaes_ES
dc.subjectcervical canceres_ES
dc.subjectoral contraceptivees_ES
dc.titleOral Contraceptives and Cervical Cancer Risk in Costa Rica: Detection Bias or Causal Associationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1001/jama.1988.03720010037037.
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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