Listar Microbiología por título
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Phospholipase A2 myotoxins from Bothrops snake venoms
(1995-11)The genus Bothrops is distributed over all Latin America, From Mexico to Argentina, and comprises nearly 31 species of snake. In most of these countries, Bothrops spp. cause the majority of snake bit envenomations, which ... -
Phospholipase A2 myotoxins from Bothrops snake venoms [Artículo de revisión]
(1995-11)Several myotoxins have been isolated from Bothrops snake venoms during the last 10 years. All of them are group II basic phospholipases A2, although some lack enzymatic activity (i.e. Lys-49 variants). These myotoxins ... -
Phospholipases A2 From Viperidae Snake Venoms: How do They Induce Skeletal Muscle Damage?
(Acta Chim. Slov., 58, 647–659, 2011, 2011)Phospholipases A2 (PLA2s) are abundant components in snake venoms, which play important toxic roles. This review focuses on group II PLA2s endowed with myotoxic effects, present in Viperidae venoms. These PLA2s are ... -
Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms
(Biochimica et Biophysica Acta - Biomembranes vol 1848: 463–468, 2015-02)We describe the interaction of various phospholipases A2 (PLA2) from snake venoms of the family Viperidae (Macrovipera lebetina obtusa, Vipera ursinii renardi, Bothrops asper) with giant unilamellar vesicles (GUVs) composed ... -
Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins
(2013-02)Phospholipases A2 (PLA2s) are abundant components of snake venoms, where they play toxic and digestive roles. Despite having a similar three-dimensional structure, venom PLA2s exert an amazing variety of toxic and ... -
Phylogenetic analyses of antibiotic-producing Streptomyces sp. isolates obtained from the stingless-bee Tetragonisca angustula (Apidae: Meliponini)
(2019)Many insects have been associated with actinobacteria in protective symbiosis where antimicrobial metabolites inhibit host pathogens. However, the microbiota of neotropical insects such as the stingless-bee Tetragonisca ... -
Physical characteristics of nano-Hydroxyapatite Pickering-emulsions and their adjuvant activity on the antibody response towards the Bothros asper snake venom
(2019)Emulsions are crucial in the treatment of snake bites to bust the antibody response of the inmunogen. The widely used Freund's emulsion typically combines 50/50 water-oil (W/O) phase. However, its use is limited because ... -
Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed
(2017-03)Jicaro (Crescentia alata) is a tropical tree native to Mesoamerica well adapted to severe drought conditions. The seeds of the fruits were analyzed for protein, fatty acid, dietary fiber, phytate, polyphenol, tannin, ... -
Pitfalls to avoid when using phage display for snake toxins
(2017-02)Antivenoms against bites and stings from snakes, spiders, and scorpions are associated with immunological side effects and high cost of production, since these therapies are still derived from the serum of hyper-immunized ... -
Plan de mejora de procesos de fase preanalítica en el laboratorio clínico “Clodomiro Picado Twight” del Hospital San Juan de Dios de Costa Rica durante el período diciembre 2022-abril 2023
(2023)Introducción: Los laboratorios clínicos constituyen establecimientos que llevan a cabo análisis a muestras de índole biológico. El procesamiento se encuentra dividido en tres fases: la fase preanalítica, la fase analítica ... -
Plan para la implementación de tetanalgesia como método de analgesia no farmacológica en procedimientos de extracción sanguínea en el Laboratorio Clínico del Hospital Nacional de Niños de la Caja Costarricense de Seguro Social
(2023)Los recién nacidos y lactantes pequeños son capaces de experimentar dolor desde la semana veinticinco de edad gestacional. Recientemente, se han estudiado mecanismos alternativos a los fármacos analgésicos que estimulan ... -
Plan para la implementación del modelo de gestión de calidad EFQM en el Laboratorio Clínico y Banco de Sangre de la Universidad de Costa Rica para su mejora continua en el año 2023
(2023-07)El Laboratorio Clínico y Banco de Sangre de la Universidad de Costa Rica cuenta con más de 15 años de experiencia en el manejo de la calidad bajo el modelo de gestión ISO, el cual es complementario al EFQM, ya que el primero ... -
Plasma lipid levels in 10-to 13-year old Costa Rican elementary schoolchildren
(2000-09)An adverse lipid profile is a major risk factor for atherosclerosis. This study evaluated the lipid profiles of 683 schoolchildren aged 10 to 13 years. The prevalence of both high LDL and high total cholesterol levels was ... -
Plasmidos de virulencia
(Revista Médica del Hospital Nacional de Niños Dr. Carlos Sáenz Herrera 130(I): 11-22, 1978)Se revisan conceptos bisicos sobre los plasmidosdesoxirribonucleico extracromosomico con mplicacion autonoma— prisentee en el citoplasma bacte. riano. Se hace infasis en plismidos qua codifican factor's de virulencia como ... -
Plataforma bioinformática para la identificación de nuevas inferencias del fenómeno de compensación de dosis génica en el panel NCI-60
(2021-12)Las células generan transcritos en respuesta a estímulos internos y externos, siendo algunos codificantes de proteínas y otros no codificantes. Los transcritos que codifican proteínas son regulados por varios elementos, ... -
Poblaciones larvales de Califóridos como estimadores del intervalo post-mortem en un modelo experimental
(2003-12-31)Con el fin de estimar el intervalo post-mortem (IPM) basado en análisis poblacionales de larvas de califóridos, conejos de la cepa New Zealand (3,8 kg) fueron sometidos a eutanasia en abril, julio y octubre de 2002 y enero ... -
Polyspecific snake antivenom may help in antivenom crisis
(2003-02)In Africa snakebites cause thousands of deaths annually and much permanent physical disability, but the supply of antivenom, the only specific treatment, is threatened by commercial pressures and privatisation. This has ... -
Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves
(PLoS ONE 6(5): e19834, 2011-05-24)Background: Viperid snakebite envenoming is characterized by prominent local tissue damage, including muscle necrosis. A frequent outcome of such local pathology is deficient skeletal muscle regeneration, which causes ... -
Population Genomics Insights into Adaptive Evolution and Ecological Differentiation in Streptomycetes
(2019)Deciphering the genomic variation that represents microevolutionary processes toward species divergence is key to understanding microbial speciation, which has long been under debate. Streptomycetes are filamentous bacteria ... -
Porcentaje y cifra absoluta de linfocitos T en sangre periférica por el método de rosetas E: estudio de cuarenta adultos sanos
(1985)Se realizó la determinación del porcentaje y cifra absoluta de linfocitos T en sangre periférica a un grupo de 40 adultos sanos costarricenses, seleccionados de un grupo inicial de 58 voluntarios. Se utilizó un método de ...