Browsing Microbiología by Title
Now showing items 556-575 of 816
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Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms
(Toxins vol.6:3388-3405, 2014-12-15)Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact worldwide, mostly affecting poor people involved in agricultural activities in Africa, Asia, Latin America and Oceania. A ... -
Ontogenetic changes in the venom of the snake Lachesis muta stenophrys (bushmaster) from Costa Rica
(1990)A comparative study was performed on some enzymatic and toxic activities of venoms collected from newborn, one-year old, two-years old and adult (more than five-years old) specimens of Lachesis muta stenophrys. There was ... -
Ontogenetic variability of Bothrops atrox and Bothrops asper snake venoms from Colombia
(2003-09)The lancehead snakes Bothrops asper and Bothrops atrox inflict 70–90% of the 3000 bites reported every year in Colombia. In this work, the venoms of B. atrox from Meta (Villavicencio, 33 specimens) and B. asper from Antioquia ... -
Optimización de un método colorimétrico para la cuantificación de cobre en suero
(1993)Se optimizó y adaptó un método colorimétrico para la determinación de cobre sérico con dibenzilditiocarbamato de zinc. El método presenta linealidad por lo menos hasta 400 ug/dl de cobre. La recuperación promedio obtenida ... -
p-Bromophenacyl bromide modification of Bothrops asper myotoxin II, a lysine-49 phospholipase A2, affects its pharmacological activities
(1993-09)Modification of Bothrops asper myotoxin II, a lysine-49 phospholipase A2 variant, was carried out with p-bromophenacyl bromide. Modified toxin did not show changes in its charge and immunological properties but two of its ... -
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa
(2005-06)A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in ... -
Parasitismo imaginario: experiencia clínica y diagnóstica
(2012-06-01)Objetivo: describir los casos de parasitismo imaginario observados en el Laboratorio de Entomología Médica, Facultad de Microbiología, Universidad de Costa Rica durante 2001-2011. Métodos: se describen 9 casos cuyas ... -
La participación comunitaria como recurso para la prevención del dengue en una comunidad urbana de San José, Costa Rica
(2005-06-01)Se implementó un modelo de participación comunitaria en dos de los cuatro sectores del caserío "La Carpio ",Distrito Uruca,San José, Costa Rica,el cual constituyó el primer poblado del Gran Área Metropolitana de San José ... -
Participatory risk mapping of malaria vector exposure in northern South America using environmental and population data
(2014-03-01)Malaria elimination remains a major public health challenge in many tropical regions, including large areas of northern South America. In this study, we present a new high spatial resolution (90 × 90 m) risk map for Colombia ... -
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
(2016-09-01)The pathogenesis of dermonecrosis induced by the venom of the African spitting cobra Naja nigricollis was investigated in a mouse model. Intradermal injection of venom induced a macroscopic necrotic lesion. Histological ... -
Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice
(1986-02)The mode by which coral snake (Micrurus nigrocinctus) venom affects skeletal muscle was studied using a combined approach. The venom induced early functional and structural alterations in the plasma membrane of muscle ... -
Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms
(2013-12-15)Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments, purified from the plasma of animals immunized with snake venoms. Their therapeutic success lies in their ability to mitigate the progress ... -
Pathogenic potential of a Costa Rican strain of ‘Candidatus Rickettsia amblyommii’ in guinea pigs (Cavia porcellus) and protective immunity against Rickettsia rickettsii
(2015-07)‘Candidatus Rickettsia amblyommii’ is a spotted fever group rickettsia that is not considered pathogenic, although there is serologic evidence of possible infection in animals and humans. The aim of this study was to ... -
Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom
(2001-06)The pathological alterations induced by neuwiedase, a 22 kDa class P-I metalloproteinase from the venom of the South American pit viper Bothrops neuwiedi, were studied in mice. Neuwiedase was devoid of hemorrhagic activity ... -
Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (Terciopelo)
(1992-09)Venom from newborn Bothrops asper snakes has higher lethal, hemorrhagic, edema-forming, proteolytic and defibrinating activities than venom from adult B. asper specimens. Electrophoretic analysis confirmed the variation ... -
Pathological changes induced by BaH1, a hemorrhagic proteinase isolated from Bothrops asper (Terciopelo) snake venom, on mouse capillary blood vessels
(1994-08)The pathological changes induced in capillaries by BaH1, a hemorrhagic metalloproteinase isolated from the venom of Bothrops asper, were studied after i.m. injection in mouse gastrocnemius. Hemorrhage was observed ... -
Patogénesis y neutralización de los efectos locales inducidos por el veneno de la serpiente "terciopelo" (Bothrops asper).
(1982)Se presenta la revisión de varias investigaciones sobre la patogénesis y neutralización de los efectos locales inducidos por el veneno de la serpiente terciopelo. El cuadro local está constituido por mionecrosis, hemorragia ... -
Peligros de los falsos positivos en la determinación de gonadotropina coriónica
(2001)Los expertos del Servicio de Referencia para hCG (hormona gonadotropina coriónica humana) de los Estados Unidos de América, han llamado la atención de los laboratorios que realizan la determinación de esta hormona, para ...