Listar Microbiología por título
Mostrando ítems 297-316 de 1169
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Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping
(2017-07)Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on antibody recognition sites (epitopes) on snake venom proteins ... -
Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster”
(2017)Snake venoms from the Viperidae and Elapidae families often have several phospholipases A2 (PLA2s), which may display different functions despite having a similar structural scaffold. These proteins are considered an ... -
Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani
(1999-06-15)Lys49-Phospholipase A2 (Lys49-PLA2) homologues damage membranes by a Ca2+-independent mechanism which does not involve catalytic activity. With the aim of determining the structural basis for this novel activity, we have ... -
Crystallization and preliminary diffraction data of two myotoxins isolated from the venoms of Bothrops asper (Terciopelo) and Bothrops nummifer (jumping viper)
(1993-08)Two myotoxins isolated from B. asper (myotoxin II) and B. nummifer (myotoxin I) snake venoms have been crystallized and their diffraction properties are described. These myotoxins are phospholipase A2 variants which lack ... -
Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom
(2004-12-01)Suramin is a highly charged polysulfonated napthylurea that interferes in a number of physiologically relevant processes such as myotoxicity, blood coagulation and several kinds of cancers. This synthetic compound was ... -
Crystallization of the Lys49 PLA2 homologue, myotoxin II from the venom of Atropoides nummifer
(2004-12)Myotoxin II, a Lys49 catalytically inactive phospholipase A2 homologue from Atropoides nummifer venom, was purified, characterized and crystallized. The crystals belongs to the tetragonal system, space group P43212, with ... -
Cuantificación de formas larvales de Synthesiomyia nudiseta (Diptera: Muscidae) como un criterio en el análisis del intervalo post mortem
(2005)El número de larvas de Synthesiomyia nudiseta (Diptera: Muscidae) encontradas in cadáveres fue evaluada como un criterio para la estimación del intervalo post-mortem (IPM) en un modelo con carcasas de conejo. Conejos (New ... -
Cuantificación espectrofotométrica del cloruro en suero mediante reacción con tiocianato de mercurio
(1995)El anión que se encuentra en mayor concentración en el fluido extracelular es el ion cloruro (i) (2), por lo que juega un papel importante en regular la distribución del agua, la presión osmótica y el balance aniónico-catiónico ... -
Cuidado con la obesidad infantil y juvenil
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Culicidofauna asociada con contenedores artificiales en la comunidad “La Carpio”, Costa Rica
(2009-06-01)Objetivo: Determinar las especies de mosquitos más frecuentes en “La Carpio”, primer comunidad del Área Metropolitana de San José en sufrir un brote por dengue. Métodos: Cuatro encuestas larvales fueron ... -
Current challenges for confronting the public health problem of snakebite envenoming in Central America
(2014-03-06)Snakebite envenoming is a serious public health problem in Central America, where approximately 5,500 cases occur every year. Panama has the highest incidence and El Salvador the lowest. The majority, and most severe, cases ... -
Cytotoxicity induced in myotubes by a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper: Evidence of rapid plasma membrane damage and a dual role for extracellular calcium
(2007-12)Acute muscle tissue damage, myonecrosis, is a typical consequence of envenomations by snakes of the family Viperidae. Catalytically-inactive Lys49 phospholipase A2 homologues are abundant myotoxic components in viperid ... -
Cytotoxicity of Lachesis muta muta snake (bushmaster) venom and its purified basic phospholipase A2 (LmTX-I) in cultured cells
(2007)Human envenoming by Lachesis muta muta venom, although infrequent, is rather severe, being characterized by pronounced local tissue damage and systemic dysfunctions. Studies on the pharmacological actions of L. m. muta ... -
Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus
(2021-09)Viperid snake venoms contain a unique family of cytotoxic proteins, the Lys49 PLA2 homologs, which are devoid of enzymatic activity but disrupt the integrity of cell membranes. They are known to induce skeletal muscle ... -
Danger in the canopy: comparative proteomics and bioactivities of the venoms of the South American palm viper Bothrops bilineatus subspecies bilineatus and smaragdinus, and antivenomics of B. b. bilineatus (Rondônia) venom against the Brazilian pentabothropic antivenom
(2020)We report a structural and functional proteomics characterization of venoms of the two subspecies (Bothrops bilineatusbilineatus and B. b. smaragdinus) of the South American palm pit viper from the Brazilian state of ... -
Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis
(2015-12-01)Four specimens of the olive sea snake, Aipysurus laevis, were collected off the coast of Western Australia, and the venom proteome was characterized and quantitatively estimated by RP-HPLC, SDS-PAGE, and MALDI-TOF-TOF ... -
De las creencias de la comunidad educativa escolar sobre actividad física a las políticas institucionales del centro educativo
(2015)La originalidad de este artículo radica en contribuir a la comprensión de las creencias sobre actividad física que tiene la comunidad educativa, sustentadas en enfoques curriculares academicistas y positivistas, que rigen ... -
Degenerative and regenerative changes in murine skeletal muscle after injection of venom from the snake Bothrops asper: a histochemical and immunocytochemical study.
(1991)The degenerative and regenerative changes in murine skeletal muscle after injection of Bothrops asper venom were studied by histological, lectin histochemical and immunocytochemical techniques. According to our observations, ... -
Degradation of carbofuran by Trametes versicolor in rice husk as a potential lignocellulosic substrate for biomixtures: From mineralization to toxicity reduction
(2014-12)Biopurification systems for the treatment of pesticide-containing wastewaters contain a biomixture constituted by low-cost materials (soil, lignocellulosic substrates and humic components). In particular, the use of ...