Listar Microbiología por título
Mostrando ítems 723-742 de 1169
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MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity
(2015-02-24)GABAA receptors shape synaptic transmission by modulating Cl− conductance across the cell membrane. Remarkably, animal toxins that specifically target GABAA receptors have not been identified. Here, we report the discovery ... -
Modeling dengue cases in health Regions of Costa Rica using El Niño Southern Oscillation and local vegetation dynamics
(2009-11)Temporal behavior of dengue fever and dengue hemorrhagic fever (DH/DHF) has been associated with climate, which may modulate mosquito vector populations. El Niño Southern Oscillation (ENSO) fluctuations can be related to ... -
Modelo de lógica difusa como alternativa para la evaluación de la satisfacción de usuarios del laboratorio clínico
(2014)La calidad consiste en un conjunto de características propias de un producto a nivel de variabilidad y cumplimiento de los requerimiento del cliente, el cual también incluye el cómo se brinda el servicio a éste. Una de ... -
Modificaciones proteicas inducidas por Brucella abortus 2308W en compartimentos intracelulares tempranos de macrófagos RAW 264.7
(2019)Brucella abortus es un patógeno intracelular bacteriano causante de la brucelosis bovina, una zoonosis desatendida de gran importancia mundial. Una vez entra a la célula hospedera B. abortus transita en un compartimento ... -
Modulation of the Susceptibility of Human Erythrocytes to Snake Venom Myotoxic Phospholipases A2: Role of Negatively Charged Phospholipids as Potential Membrane Binding Sites
(2001-07-01)Cerrophidion (Bothrops) godmani myotoxins I (CGMT-I) and II (CGMT-II), Asp-49 and Lys-49 phospholipases A(2) (PLA2s), which drastically differ in enzymatic activity, were devoid of direct hemolytic effects on erythrocytes ... -
Molecular architecture of the antiophidic protein DM64 and its binding specificity to myotoxin II from Bothrops asper venom
(2022)DM64 is a toxin-neutralizing serum glycoprotein isolated from Didelphis aurita, an ophiophagous marsupial naturally resistant to snake envenomation. This 64 kDa antitoxin targets myotoxic phospholipases A2, which account ... -
Molecular Characterization of Two Major Dengue Outbreaks in Costa Rica
(2016-07)Dengue virus (DENV) (Flavivirus, Flaviviridae) is a reemerging arthropod-borne virus with a worldwide circulation, transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes. Since the first detection of its ... -
Molecular Detection of Bartonella Species in Fleas Collected from Dogs and Cats from Costa Rica
(2015-09)The bacterial genus Bartonella includes several species with zoonotic potential, some of which are common in domestic dogs and cats, as well as in their fleas. Because there is no previous information about the presence ... -
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
(2016-12-01)Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite the outbreaks ... -
Molecular Determinants of Antibiotic Resistance in the Costa Rican Pseudomonas aeruginosa AG1 by a Multi-omics Approach: A Review of 10 Years of Study
(2021)Pseudomonas aeruginosa AG1 (PaeAG1) is a Costa Rican strain that was isolated in 2010 in a major Hospital. This strain has resistance to multiple antibiotics such as β-lactams (including carbapenems), aminoglycosides, and ... -
Molecular determinants of antibiotic tolerance in the high-risk Pseudomonas aeruginosa AG1 by a multi-omics approach: from the genome to the transcriptomic network in response to ciprofloxacin
(2020)La resistencia a los antibióticos es una amenaza importante para la salud pública porque compromete la administración de una terapia antibiótica adecuada. Pseudomonas aeruginosa es un patógeno oportunista que causa infecciones ... -
Molecular epidemiology and antimicrobial resistance of Clostridium difficile in a national geriatric hospital in Costa Rica
(2018-08)Background: the epidemiology of Clostridium difficile infections (CDI) is changing rapidly worldwide; knowledge on the genotypes of C. difficile circulating in specialized geriatric hospitals and their resistance to ... -
Molecular epidemiology of Clostridium difficile infection in a Brazilian cancer hospital
(2017)Clostridium difficile is a Gram-positive spore forming anaerobic bacterium and the main cause of healthcare-associated diarrhea. This study aimed to perform the phenotypic characterization and molecular typing of Clostridium ... -
Molecular Recognition of Surface Trans-Sialidases in Extracellular Vesicles of the Parasite Trypanosoma cruzi Using Atomic Force Microscopy (AFM)
(2022-06-28)Trans-sialidases (TS) are important constitutive macromolecules of the secretome present on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in Chagas disease. These enzymes have ... -
Mortality by Hymenoptera stings in Costa Rica, 1985-2006
(2009)Objective. To analyze mortality due to Hymenoptera stings in Costa Rica during 1985–2006. Methods. Records of deaths due to Hymenoptera stings in 1985–2006 were retrieved from Instituto Nacional de Estadística y Censos ... -
Mortality due to snakebite envenomation in Costa Rica (1993–2006)
(2008-09-01)The mortality due to snakebite envenomation in Costa Rica for the period 1993–2006 was investigated by a retrospective analysis. There were 48 fatalities due to snakebites during this period. Mortality rates ranged from ... -
Multidrug‑Resistant Escherichia coli in Costa Rican Domestic Wastewater Treatment Plants Maintains Horizontal Transfer Capacity of Resistance Determinants in Effluents
(2023-06-13)This study was conducted to evidence the dissemination potential of antibiotic resistance genetic elements in E. coli isolates of Costa Rican domestic wastewater treatment plants (WWTPs). Few studies have addressed ... -
Multiple paths to aquatic specialisation in four species of Central American Anolis lizards
(2015-02-26)Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic ... -
Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins – distinct mechanisms of action
(2013-07-12)Bothrops snakes are the major cause of ophidian envenomings in Latin America. Their venom contains myotoxins that cause prominent muscle damage, which may lead to permanent disability. These toxins include myotoxins Mt-I ... -
Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis
(2016-04-01)The time-course of the pathological effects induced by the venom of the snake Bothrops asper in muscle tissue was investigated by a combination of histology, proteomic analysis of exudates collected in the vicinity of ...