Browsing Microbiología by Author "Nasidi, Abdulsalami"
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A new Pan African polyspecific antivenom developed in response to the antivenom crisis in Africa
Laing, Gavin D.; Renjifo, J.M.; Ruiz, F.; Harrison, Robert A.; Nasidi, Abdulsalami; Gutiérrez, José María; Rowley, Paul D.; Warrell, David A.; Theakston, R. David G. (2003-07)Currently there is a crisis in the supply of antivenom for treatment of snake bite in sub-Saharan Africa. Commercial pressures have resulted in the reduction or even cessation of production of antivenom by European ... -
Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa
Calvete Chornet, Juan José; Cid, Pedro; Sanz, Libia; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Herrera Vega, María; León Montero, Guillermo; Harrison, Robert A.; Durfa, Nandul; Nasidi, Abdulsalami; Theakston, R. David G.; Warrell, David A.; Gutiérrez, José María (2010)The immunoreactivity of EchiTAb-Plus-ICP, an antivenom developed for the treatment of snakebite envenoming in sub-Saharan Africa, to venoms of seven Echis and Bitis species, was assessed by “antivenomics.” This proteomic ... -
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa
Gutiérrez, José María; Rojas Umaña, Ermila; Quesada, L.; León Montero, Guillermo; Núñez, Javier; Laing, Gavin D.; Sasa Marín, Mahmood; Renjifo, J.M.; Nasidi, Abdulsalami; Warrell, David A.; Theakston, R. David G.; Rojas Céspedes, Gustavo (2005-06)A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in ... -
Polyspecific snake antivenom may help in antivenom crisis
Laing, Gavin D.; Harrison, Robert A.; Theakston, R. David G.; Renjifo, J.M.; Nasidi, Abdulsalami; Gutiérrez, José María; Warrell, David A. (2003-02)In Africa snakebites cause thousands of deaths annually and much permanent physical disability, but the supply of antivenom, the only specific treatment, is threatened by commercial pressures and privatisation. This has ... -
Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa
Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Herrera Vega, María; León Montero, Guillermo; Harrison, Robert A.; Durfa, Nandul; Nasidi, Abdulsalami; Calvete Chornet, Juan José; Theakston, R. David G.; Warrell, David A.; Gutiérrez, José María (2010-02)A preclinical assessment was performed on the neutralizing efficacy of a whole IgG polyspecific antivenom (EchiTAb-Plus-ICP®), designed for the treatment of snakebite envenomings in Nigeria. It was generated by immunizing ... -
Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutralization Approaches
Petras, Daniel; Sanz, Libia; Segura Ruiz, Álvaro; Herrera Vega, María; Villalta Arrieta, Mauren; Solano, Daniela; Vargas Arroyo, Mariángela; León Montero, Guillermo; Warrell, David A.; Theakston, R. David G.; Harrison, Robert A.; Durfa, Nandul; Nasidi, Abdulsalami; Gutiérrez, José María; Calvete Chornet, Juan José (2011)Venomic analysis of the venoms of Naja nigricollis, N. katiensis, N. nubiae, N. mossambica, and N. pallida revealed similar compositional trends. The high content of cytotoxins and PLA2s may account for the extensive tissue ...