Listar Microbiología por procedencia "UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Centro de Investigación en Enfermedades Tropicales (CIET)"
Mostrando ítems 1-20 de 216
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A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation
(2016-11-09)Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ... -
A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements
(2017-01)The antimicrobial resistance (AMR) rates and levels recorded for Clostridium difficile are on the rise. This study reports the nature, levels, diversity, and genomic context of the antimicrobial resistance of human C. ... -
A first perturbome of Pseudomonas aeruginosa: Identification of core genes related to multiple perturbations by a machine learning approach
(2021)Tolerance to stress conditions is vital for organismal survival, including bacteria under specific environmental conditions, antibiotics, and other perturbations. Some studies have described common modulation and shared genes ... -
A fluorescence-activatable reporter of flavivirus NS2B–NS3 protease activity enables live imaging of infection in single cells and viral plaques
(2020-01-09)The genus Flavivirus in the family Flaviviridae comprises many medically important viruses, such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus. The quest for thera- peutic targets to combat flavivirus ... -
A Fluorescent Real-Time Plaque Assay Enables Single-Cell Analysis of Virus-Induced Cytopathic Effect by Live-Cell Imaging
(2021-06-22)Conventional plaque assays rely on the use of overlays to restrict viral infection allowing the formation of distinct foci that grow in time as the replication cycle continues leading to countable plaques that are ... -
A geographical sampling method for surveys of mosquito larvae in an urban area using high-resolution satellite imagery
(2008-06-01)Entomological surveys in urban areas are often biased by selecting houses or locations with known high vector densities. A sampling strategy was developed for Puntarenas, Costa Rica, using high-resolution satellite imagery. ... -
A geographical sampling strategy for field surveys in an urban area using high-resolution satellite imagery
(2006-11)Field evaluations for studying the epidemiology of vector-borne diseases like dengue in urban areas are often restricted to selection of households and buildings for field surveys. Therefore, the resulting sampling frame ... -
A hybrid mathematical modeling approach of the metabolic fate of a fluorescent sphingolipid analogue to predict cancer chemosensitivity
(2018-06)Sphingolipid (SL) metabolism is a complex biological system that produces and transforms ceramides and other molecules able to modulate other cellular processes, including survival or death pathways key to cell fate ... -
A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption
(2016-08)The epidemiology of Clostridium difficile infections is highly dynamic as new strains continue to emerge worldwide. Here we present a detailed analysis of a new C. difficile strain (ICC-45) recovered from a cancer patient ... -
A Novel Green Chemistry Method for Nonaqueous Extraction and High-Performance Liquid Chromatography Detection of First-, Second-, and Third-Generation Tetracyclines, 4-Epitetracycline, and Tylosin in Animal Feeds
(2012-06)Although tetracyclines and macrolides are common additives for animal nutrition, methods for their simultaneous determination in animal feeds are nonexistent. By coupling an organic extraction and solid-phase extraction ... -
A review of the genus Rickettsia in Central America
(2018)In this paper, we present a historical review of rickettsiosis in Central America and also the most recent findings of Rickettsia in ectoparasites. All countries of Central America have records of rickettsiosis. Regarding ... -
A single exposure of sediment sulphate-reducing bacteria to oxytetracycline concentrations relevant to aquaculture enduringly disturbed their activity, abundance and community structure
(2015-05)Aim: although feed medicated with antibiotics is widely used in animal production to prevent and treat bacterial infections, the effect of these drugs on nontarget anaerobic bacteria is unknown. We aimed to clarify whether ... -
Acanthamoeba genotype T4 keratitis in a patient with Thygeson’s superficial punctate keratitis
(2017-01)A case of amoebic keratitis due to Acanthamoeba genotype T4 is reported. The patient is a 74-year old woman with Thygeson’s superficial punctate keratitis. Corneal scrapings were employed for the diagnosis, which included ... -
Aedes albopictus (Skuse) en la Región Huetar Atlántica de Costa Rica: estudios preliminares sobre ecología larval
(2012)Objetivo: Determinar las características de los hábitats larvales de Ae. albopictus y su culicidofauna asociada en la comunidad “La Primavera”. Métodos: Se realizó una encuesta larval en 20 de 28 casas ubicadas en un área ... -
Alterations in common marmoset gut microbiome associated with duodenal strictures
(2022-03-28)Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets (Callithrix jacchus). Despite standardized housing, diet and husbandry, a recently described gastrointestinal syndrome ... -
Amebas de vida libre como agentes de encefalitis en el ser humano
(2014-07)Este artículo de revisión se enfoca en las amebas de vida libre, un tipo de protozoarios que habitan diferentes tipos de suelo y fuentes de agua. Estos organismos tienen dos estadios evolutivos: trofozoíto y quiste, siendo ... -
An update on the detection and treatment of Rickettsia felis
(2012-05-22)Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is currently reported in 18 countries in all continents. The distribution of this species is worldwide, determined by the ... -
Analysis of gut microbiome profiles in common marmosets (Callithrix jacchus) in health and intestinal disease
(2022-03-15)Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets. To understand the role of the microbiome in GI diseases, we characterized the gut microbiome of 91 healthy marmosets (303 ... -
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
(2016-03)Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ... -
Análisis Bibliométrico de las publicaciones generadas por la Facultad de Microbiología de la Universidad de Costa Rica, 2002-2005
(2010-07)En el presente estudio se realizó un análisis bibliométrico de la producción científica de los docentes de la carrera de Licenciatura en Microbiología y Química Clínica de la Universidad de Costa Rica durante el período ...