• Antivenoms for Snakebite Envenomings 

      Gutiérrez, José María; León Montero, Guillermo; Lomonte, Bruno; Angulo Ugalde, Yamileth (2011-10)
      Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake ...
    • Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms 

      León Montero, Guillermo; Herrera Vega, María; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Vargas Arroyo, Mariángela; Gutiérrez, José María (2013-12-15)
      Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments, purified from the plasma of animals immunized with snake venoms. Their therapeutic success lies in their ability to mitigate the progress ...
    • Pros and cons of different therapeutic antibody formats for recombinant antivenom development 

      Laustsen, Andreas Hougaard; Gutiérrez, José María; Knudsen, Cecilie; Johansen, Kristoffer H.; Bermúdez Méndez, Erick; Cerni, Felipe A.; Jürgensen, Jonas A.; Ledsgaard, Line; Martos Esteban, Andrea; Øhlenschlæger, Mia; Pus, Urska; Andersen, Mikael Rørdam; Lomonte, Bruno; Engmark, Mikael Gerling; Pucca, Manuela Berto (2018-05)
      Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by the many advances in immunology, synthetic biology, and antibody research, different approaches and antibody formats are being ...