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Phosphatidylinositol 3-Kinase/Akt Pathway Targets Acetylation of Smad3 through Smad3/CREB-binding Protein Interaction: Contribution to transforming growth factor 1-induced epstein-barr virus reactivation
(THE JOURNAL OF BIOLOGICAL CHEMISTRY 284(36), pp. 23912–23924, 2009-09-04)
Epstein-Barr virus, a ubiquitous human herpesvirus, is associated with the development of carcinomas and lymphomas. We previously showed that transforming growth factor 1 (TGF- 1) mediated the virus to enter the lytic ...
Relation of atrophic gastritis with Helicobacter pylori-CagA+ and interleukin-1 polymorphisms
(World Journal Gastroenterol 14(42), 2008-11-14)
AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory polymorphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a ...
Activation of the lytic program of the Epstein–Barr virus in Burkitt's lymphoma cells leads to a two steps downregulation of expression of the proapoptotic protein BimEL, one of which is EBV-late-gene expression dependent
(Virology 387 (2009) (1) p.41.49, 2009-02-28)
The Epstein–Barr virus (EBV) generally latently infects its target cells with expression of genes conferring resistance to apoptosis. However, the modulation of apoptotic signals during lytic cycle remains poorly understood. ...
Epstein-Barr Virus (EBV) Genome and Expression in Breast Cancer Tissue: Effect of EBV Infection of Breast Cancer Cells on Resistance (Taxol)
(Journal of Virologia 80(2) p 845-853., 2006-01)
The Epstein-Barr virus (EBV) has been detected in subsets of breast cancers. In order to elaborate on these
observations, we quantified by real-time PCR (Q-PCR) the EBV genome in biopsy specimens of breast cancer
tissue ...