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A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms
(1999-06)
A randomized blinded clinical trial was performed in 53 patients bitten by Bothrops sp. and Porthidium sp. in Antioquia and Chocó, Colombia, in order to compare the efficacy and safety of two antivenoms made of whole IgG ...
Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica
(2000-10)
A study was performed on the ability of antivenoms, produced in Brazil and Costa Rica, to neutralize lethal, hemorrhagic and coagulant activities of the venoms of 16 species of Central and South American snakes of the ...
Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America
(1996)
De nombreuses envenimations ophidiennes en Amérique centrale sont dues aux crotales (famille des Viperidae) parmi lesquels Bothrops asper est le principal responsable. Quelques accidents sont provoqués par les serpents ...
Effect of storage temperature on the stability of polyvalent antivenom produced in Costa Rica.
(1990)
The effect of storage temperature on the stability of the liquid polyvalent (crotaline) antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was studied during a twelve-month period. The following parameters ...
Envenamiento por mordedura de serpiente en Costa Rica en 1996: Epidemiología y consideraciones clínicas
(1999-12)
El presente trabajo se efectúa para tener una visión actualizada y completa de las principales características epidemiológicas del envenenamiento por mordedura de serpiente en Costa Rica. Asimismo, se incluyen algunas ...
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa
(2005-06)
A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in ...
Ability of a polyvalent antivenom to neutralize the venom of Lachesis muta melanocephala, a new Costa Rican subspecies of the bushmaster
(1987)
Several toxic and enzymatic activities of the venom of L. m. melanocephala were studied. This venom has many similarities with that of L. m. stenophrys, although there are quantitative differences in venom activities, as ...
Comparative study on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom
(1999-08)
A comparative study was performed on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic activities of Micrurus nigrocinctus venom. Both antivenoms were adjusted to a similar neutralizing potency ...
Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom
(1998-11)
Local tissue damage represents a serious consequence of Bothrops asper envenomations. It encompasses a complex series of alterations, including myonecrosis, dermonecrosis, hemorrhage and edema. Due to its rapid development ...
Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom
(2000-02)
The ability of sheep antivenoms, consisting of whole IgG molecules or Fab fragments, to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper venom was comparatively studied in mice. The two antivenoms ...