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First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis 

Lomonte, Bruno; Mora Obando, Diana; Fernández Ulate, Julián; Sanz, Libia; Pla Ferrer, Davinia; Gutiérrez, José María; Calvete Chornet, Juan José (Toxicon vol 93:144–154, 2015-01)
Bothriechis nigroviridis is an arboreal Neotropical pitviper found in Costa Rica and Panam a. A previous proteomic profiling of its venom revealed the presence of proteins with homology to the A and B subunits of ...

Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids 

Fernández Ulate, Julián; Vargas Vargas, Nancy; Pla Ferrer, Davinia; Sasa Marín, Mahmood; Rey Suárez, Paola; Sanz, Libia; Gutiérrez, José María; Calvete Chornet, Juan José; Lomonte, Bruno (2015-12-01)
Protein composition, toxicity, and neutralization of the venoms of Micrurus alleni and Micrurus mosquitensis, two sympatric monadal coral snakes found in humid environments of the Caribbean region of Costa Rica, were ...
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Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom 

Lomonte, Bruno; Pla Ferrer, Davinia; Sasa Marín, Mahmood; Tsai, Wan-Chih; Solórzano López, Alejandro; Ureña Diaz, Juan M.; Fernández Montes de Oca, María Laura; Mora Obando, Diana; Sanz, Libia; Gutiérrez, José María; Calvete Chornet, Juan José (Journal of Proteomics Volume 103, 30 May 2014, Pages 137–152, 2014-05-30)
The yellow-bellied sea snake, Pelamis platura, is the most broadly distributed snake species. Despite being endowed with a highly lethal venom, a proteomic analysis of its toxin composition was unavailable. The venoms of ...
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Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms 

Calvete Chornet, Juan José; Sanz, Libia; Pla Ferrer, Davinia; Lomonte, Bruno; Gutiérrez, José María (Toxins vol.6:3388-3405, 2014-12-15)
Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact worldwide, mostly affecting poor people involved in agricultural activities in Africa, Asia, Latin America and Oceania. A ...

Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics 

Gutiérrez, José María; Solano Trejos, María Gabriela; Pla Ferrer, Davinia; Herrera Vega, María; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Vargas Arroyo, Mariángela; Sanz, Libia; Lomonte, Bruno; Calvete Chornet, Juan José; León Montero, Guillermo (2013-07)
The assessment of the capacity of antivenoms to neutralize the lethal activity of snake venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely performed by manufacturers and quality ...

Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays 

Gutiérrez, José María; Tsai, Wan-Chih; Pla Ferrer, Davinia; Solano Trejos, María Gabriela; Lomonte, Bruno; Sanz, Libia; Angulo Ugalde, Yamileth; Calvete Chornet, Juan José (2013-03-15)
A polyspecific antivenom is used in Central America for the treatment of envenomings by viperid snakes. This antivenom is generated in horses hyperimmunized with a mixture of venoms from Bothrops asper, Crotalus simus and ...
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Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead 

Solano Trejos, María Gabriela; Pla Ferrer, Davinia; Herrera Vega, María; Segura Ruiz, Álvaro; Vargas Arroyo, Mariángela; Villalta Arrieta, Mauren; Sánchez Brenes, Andrés; Sanz, Libia; Lomonte, Bruno; León Montero, Guillermo; Calvete Chornet, Juan José; Gutiérrez, José María (2017-05)
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. The efficacy of antivenoms to neutralize toxicity of medically-relevant snake venoms has to be demonstrated through meticulous ...

Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses 

Lomonte, Bruno; Rey Suárez, Paola; Fernández Ulate, Julián; Sasa Marín, Mahmood; Pla Ferrer, Davinia; Vargas Vargas, Nancy; Bénard Valle, Melisa; Sanz, Libia; Corrêa Netto, Carlos; Núñez Rangel, Vitelbina; Alape Girón, Alberto; Alagón Cano, Alejandro; Gutiérrez, José María; Calvete Chornet, Juan José (2016-11)
The application of proteomic tools to the study of snake venoms has led to an impressive growth in the knowledge about their composition (venomics), immunogenicity (antivenomics), and toxicity (toxicovenomics). About ...

Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms 

Calvete Chornet, Juan José; Gutiérrez, José María; Sanz, Libia; Pla Ferrer, Davinia; Lomonte, Bruno (2015-03)
Envenoming following snakebite is largely a neglected threat to public health in tropical and subtropical regions of Africa, Asia, Latin America and Oceania addicting some of the world’s poorest rural communities. An ...

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AuthorCalvete Chornet, Juan José (9)
Gutiérrez, José María (9)
Lomonte, Bruno (9)
Pla Ferrer, Davinia (9)
Sanz, Libia (9)
Fernández Ulate, Julián (3)Sasa Marín, Mahmood (3)Solano Trejos, María Gabriela (3)Herrera Vega, María (2)León Montero, Guillermo (2)... View MoreTypeArtículo científico (7)info:eu-repo/semantics/article (7)Capítulo de libro (1)info:eu-repo/semantics/bookPart (1)info:eu-repo/semantics/preprint (1)Preprint (1)ProcedenceVicerrectoría de Investigación (9)Vicerrectoría de Docencia (2)... View MoreHas File(s)Yes (9)

  • Repositorios universitarios

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