Now showing items 1-10 of 47
Individual differences in the immobility behavior in juvenile and adult rats are associated with monoaminergic neurotransmission and with the expression of corticotropin-releasing factor receptor 1 in the nucleus accumbens
(Behavioural Brain Research, Vol. 252. pp. 77-87, 2013)
The study of individual differences provides an important methodological approach to analyze the neurobehavioral spectrum of a given cohort in order to understand brain function and disease. Based on immobility time in ...
Individual Differences In The Forced Swimming Test And The Effect Of Environmental Enrichment: Searching For An Interaction
(Neuroscience 265(1):95-107, 2014-02-05)
Animals with low and high immobility in the forced swimming test (FST) differ in a number of neurobehavioral factors. A growing body of evidence suggests that the exposure to enriched environments mediates a number ...
Individual differences in the forced swimming test and neurochemical kinetics in the rat brain
(Physiology & Behavior 126(1):60-69, 2014-02-08)
Individual differences in the forced swimming test (FST) could be associatedwith differential temporal dynamics of gene expression and neurotransmitter activity. We tested juvenile male rats in the FST and classified ...
Testing experience and environmental enrichment potentiated open-field habituation and grooming behaviour in rats
In laboratory rats, one of the most used paradigms to assess habituation to novelty is the open-field test. Environmental enrichment has proved to be a reliable way to enhance open-field test habituation. Experiment 1, ...
A Protocol to Perform Systemic Lipopolysacharide (LPS) Challenge in Rats
Protocolo para realizar reto sistémico con lipopolisacárido (LPS) en ratas
Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria. In animals, intraperitoneal administration of LPS, stimulates innate immunity and the production of ...
The effects of environmental enrichment and social isolation and their reversion on anxiety and fear conditioning
Animal models of fear and anxiety provide important insight into anxiety-related symptoms in humans. Environmental physical conditions and social contact influence behavior and brain plasticity particularly at early ...
La fragilidad de la memoria: creencias falsas y memoria autobiográfica, una revisión preliminar
Fragility in Memory: False Beliefs and Autobiographical Memory, a Preliminary Review
La memoria es un proceso reconstructivo, donde distintos recuerdos buscan conformar una narrativa autobiográfica coherente. No obstante, dichos recuerdos no son completamente precisos, ya que en diversas investigaciones ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Early behavioral changes after nigro-striatal system damage can serve as predictors of striatal dopamine depletion
1. Rats which had received a unilateral injection of 6-OHDA into the substantia nigra were assigned to four lesion groups according to the degree of DA depletion in the neostriatum. In these animals, behavioral changes in ...