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Clinical and Genetic Analysis of Costa Rican Patients With Parkinson's Disease
(2021)
Background: Most research in genomics of Parkinson’s disease (PD) has been done
in subjects of European ancestry, leading to sampling bias and leaving Latin American
populations underrepresented. We sought to clinically ...
Estandarización de un protocolo de inmunohistoquímica para detectar microglia del cerebro de ratas de la cepa Wistar
Standarization of a protocol of immunohistochemistry for the detection of brain microglia in wistar rats
(2017-07)
Objetivo: Estandarizar un protocolo de inmunohistoquímica que se ha utilizado ampliamente en ratones de la cepa C57BL/6J para identificar microglia del sistema nervioso central en ratas de la cepa Wistar. Materiales y ...
Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats
(2006)
Developmental and social factors are known to play a crucial role in the pathogenesis of affective disorders. Although it has been demonstrated that early life aversive experiences can be a risk factor in the development ...
Behavioral asymmetries and recovery in rats with different degrees of unilateral striatal dopamine depletion
(1994-11)
A detailed behavioral analysis during the first postoperative week was performed in rats which had sustained various degrees of unilateral neostriatal dopamine (DA) lesions by administration of the neurotoxin 6-hydroxydopamine ...
Diferencias individuales en modelos animales: un enfoque para el estudio de factores neurobiológicos relacionados con depresión
Individual differences in animal models: an approach to study neurobiological factors related to depression
(2014)
El estudio de las diferencias individuales en la prueba de nado forzado (PNF) en ratas permite la identificación
de factores de susceptibilidad o de resistencia en el desarrollo conductas relacionadas con la depresión. ...
Behavioral and neurochemical characterization of maternal care effects on juvenile Sprague–Dawley rats
(2013)
Maternal care represents a major constituent of early life environment and has the potential to modulate critical
neurobehavioral responses to stress. The aim of the present study was to determine the effects of naturally ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
(2017-05-30)
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Un método simple para la recolección, extracción y medición de catecolaminas en orina de adultos mayores
A simple method to collect, extract and measure urinary catecholamines in elderly people
(2007)
La medición de catecolaminas en orina ha sido utilizada tanto para diagnóstico
como para la investigación. Este trabajo propone algunas modificaciones
y condiciones estandarizadas para llevar a cabo la recolección ...
Environmental Enrichment and Physical Exercise Attenuate the Depressive-Like Effects Induced by Social Isolation Stress in Rats
(2020)
We assessed the antidepressant-like effects of environmental enrichment (EE) and
physical exercise (PE) compared with the selective serotonin reuptake inhibitor
fluoxetine against the depression-related neurobehavioral ...
Ejercicio y algunos mecanismos moleculares que subyacen a una mejora del desempeño en tareas cognitivas
Exercise and some molecular mechanisms that underlie performance increase on cognitive tasks
(2020)
Potenciar el aprendizaje y la memoria se ha convertido en una tarea de
interés para muchos investigadores. Artículos recientes han podido comprobar
que el ejercicio es una clara herramienta para mejorar capacidades ...