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Diferencias individuales en modelos animales: un enfoque para el estudio de factores neurobiológicos relacionados con depresión
Individual differences in animal models: an approach to study neurobiological factors related to depression
(2014)
El estudio de las diferencias individuales en la prueba de nado forzado (PNF) en ratas permite la identificación
de factores de susceptibilidad o de resistencia en el desarrollo conductas relacionadas con la depresión. ...
Behavioral and neurochemical characterization of maternal care effects on juvenile Sprague–Dawley rats
(2013)
Maternal care represents a major constituent of early life environment and has the potential to modulate critical
neurobehavioral responses to stress. The aim of the present study was to determine the effects of naturally ...
Environmental Enrichment and Physical Exercise Attenuate the Depressive-Like Effects Induced by Social Isolation Stress in Rats
(2020)
We assessed the antidepressant-like effects of environmental enrichment (EE) and
physical exercise (PE) compared with the selective serotonin reuptake inhibitor
fluoxetine against the depression-related neurobehavioral ...
Neurobiología de la depresión
(2009)
La depresión es una enfermedad compleja que afecta a un porcentaje considerable de la población mundial (17-20%). Aunque todavía no se han identificado los circuitos cerebrales específicos, investigaciones utilizando ...
Efectos del cuidado materno temprano en el desarrollo del sistema nervioso
(2013)
Ambientes adversos tempranos pueden afectar el desarrollo del sistema nervioso e incluso favorecer la
aparición de desórdenes del estado de ánimo como la depresión y ansiedad. Esta hipótesis ha sido
corroborada a través ...
Maternal behavior as an early modulator of neurobehavioral offspring responses by Sprague-Dawley rats
(2013)
Maternal care plays an important role as an early modeler of neurodevelopment and brain function,
and its effects remain until adulthood. Such modeling or programming has shown to influence the
stress response and ...
Individual differences in the immobility behavior in juvenile and adult rats are associated with monoaminergic neurotransmission and with the expression of corticotropin-releasing factor receptor 1 in the nucleus accumbens
(Behavioural Brain Research, Vol. 252. pp. 77-87, 2013)
The study of individual differences provides an important methodological approach to analyze the
neurobehavioral spectrum of a given cohort in order to understand brain function and disease. Based
on immobility time in ...
Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats
(2019-11)
The chronic unpredictable stress (CUS) paradigm is extensively used in preclinical research. However,
CUS exhibits translational inconsistencies, some of them resulting from the use of adult rodents,
despite the evidence ...
Fat Intake and obesity-related parameters predict striatal BDNF gene expression and dopamine metabolite levels in cafeteria diet-fed rats
(2022-04)
Modern westernized diet is a major risk factor associated with the current obesity epidemic. To study the effects of dietary choices of Western societies, the cafeteria diet has been validated as a preclinical model of ...