Listar Farmacia por autor "Castillo Henríquez, Luis"
Mostrando ítems 1-7 de 7
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Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ... -
Design of experiments assessment for the determination of moisture content in five herbal raw materials contained in tea products
Castillo Henríquez, Luis; Baltodano Viales, Eleaneth; Ramírez Arguedas, Nils Antonio; Vargas Zúñiga, Rolando; Hanley, Georgia (2020-02)Research interest in natural raw materials is rapidly growing due to the high demand for natural products like herbal teas. Their quality control has a direct impact on safety and efficacy. The aim of this study was to ... -
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2019)Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines the conditions under which this variable of interest can be optimized. In ... -
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Madrigal Redondo, German; Carazo Berrocal, Gustavo; Hanley Vargas, Georgia (2019-11-08)The aim of this study is to determine the impact caused by direct compression on the crystalline state of two prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ... -
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Madrigal Redondo, German; Calvo Guzmán, Briner; Baltodano Viales, Eleaneth (2019)The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. Methods: According to a ... -
Furosemide Diuretic Activity Evaluation in Female Sprague-Dawley Rats
Castillo Henríquez, Luis; Campos Cerdas, Andrea; Chacón Durán, Rebeca (2019)This research article focuses on the evaluation of the diuretic activity of Furosemide administered to a group of female Sprague Dawley rats, through the use of metabolic boxes. Methods: A hydration volume of 5 mL/100 g ... -
Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant evaluations that should be done. As we know, different crystal forms from the same molecule have differences in terms of their ...