Listar Biología por procedencia "UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones en Productos Naturales (CIPRONA)"
Mostrando ítems 1-20 de 43
-
Aceites esenciales, fenología e interacciones bióticas de la planta invasora Crassocephalum crepidioides (Asteraceae) en Costa Rica
(2022-12)Crassocephalum crepidioides (Asteraceae) es una especie herbácea con notables usos etnobotánicos en África y otras áreas, que se extendió como invasora en varias regiones tropicales y subtropicales del mundo. Objetivo: ... -
Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts
(2015)Methods to identify the bioactive diversity within natural product extracts (NPEs) continue to evolve. NPEs constitute complex mixtures of chemical substances varying in structure, composition, and abundance. NPEs can ... -
Alkaloids from Crinum erubescens Aiton
(2016-09)Eight alkaloids have been identified from fresh leaves of Crinum erubescens (Amaryllidaceae) collected in Costa Rica. The alkaloid 1-epidemethylbowdensine, detected by means of GC–MS as part of a global Amaryllidaceae ... -
Análisis de un jugo de mora (Rubus adenotrichos) endulzado con estevia (Stevia rebaudina Bertoni), una aproximación metabolómica
(2017)La investigación tuvo como propósito analizar, a través de una aproximación de estudio metabolómico, la composición integral de un jugo microfiltrado a base de mora (Rubus adenotrichos), endulzado con hojas deshidratadas ... -
Antifungal compounds
(2013-06-03)Compounds of formula (I) or formula (II), compositions and methods useful for treating and/or preventing a fungal infections are provided. wherein the substituents are as defined in the appended claims. -
Aposematismo en la rana Phyllobates vittatus (anura: Dendrobatidae): integrando defensas, señales y riesgo de depredación
(2019-10-01)El aposematismo es una estrategia defensiva en la cual animales que poseen una defensa lo advierten a los depredadores a través de una señal conspicua. Por ejemplo, algunos animales tóxicos o con poca palatabilidad le ... -
Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis
(2015)Oral squamous cell carcinoma (OSCC) is the most common cancer affecting the oral cavity, and US clinics will register about 30,000 new patients in 2015. Current treatment modalities include chemotherapy, surgery, and ... -
C1 compounds shape the microbial community of an abandoned century-old oil exploration well
(2020)The search for microorganisms that degrade hydrocarbons is highly relevant because it enables the bioremediation of these substances cheaply and without dangerous by-products. In this work, we studied the microbial communities ... -
Composition of the essential oil from leaves of Smallanthus quichensis (Asteraceae) from Costa Rica
(2015-09-30)Smallanthus is a genus of flowering plants in the Asteraceae family, which has about 24 species, ranging mostly from southern Mexico and Central America to the Andes in South America. The aim of the present study was to ... -
Current approaches to the isolation and structural elucidation of active compounds from natural products
(2018)The essence of medicinal plants, either as pure compounds or as standardized extracts, provides unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing ... -
Degree of intervention affects interannual and within-plot heterogeneity of seed arrival in tropical forest restoration
(2021-05-11)In degraded tropical landscapes, lack of seed dispersal can strongly limit recovery, and restoration interventions can overcome this barrier by attracting dispersers. However, seed dispersal patterns are typically studied ... -
Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A
(2016-05-15)Three new diketopiperazines (1–3), cyclo(l-Pro-d-trans-Hyp) (1), cyclo(l-Pro-d-Glu) (2), and cyclo(d-Pro-d-Glu) (3) and five known diketopiperazines (4–8) were isolated from the endolichenic fungus Colpoma sp. CR1465A ... -
Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
(2016-02-16)Pathogenic microorganisms often have the ability to attach to a surface, building a complex matrix where they colonize to form a biofilm. This cellular superstructure can display increased resistance to antibiotics and ... -
Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments
(2017)High-throughput screening and activity-guided purification identified nicoyamycin A, a natural product comprised of an uncommon 3-methyl-1,4-dioxane ring incorporated into a desferrioxamine-like backbone via a spiroaminal ... -
Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca2+-ATPase Inhibitors and Structure−Activity Relationships
(2015-05-20)Tricyclic clerodane diterpenes (TCDs) are natural compounds that often show potent cytotoxicity for cancer cells, but their mode of action remains elusive. A computationally based similarity search (CDRUG), combined with ... -
Essential oil composition of Ambrosia cumanensis (Asteraceae) from Costa Rica
(2015-08)Ambrosia is an Asteraceous genus of flowering plants, which has about 40-45 species, and their geographical distribution ranges from the USA, Mexico, and Central America to South America. The aim of this work was to study ... -
From dirt to industrial applications: Pseudomonas putida as a Synthetic Biology chassis for hosting harsh biochemical reactions
(2016-10)The soil bacterium Pseudomonas putida is endowed with a central carbon metabolic network capable of fulfilling high demands of reducing power. This situation arises from a unique metabolic architecture that encompasses the ... -
Fungal communities in feces of the frugivorous bat Ectophylla alba and its highly specialized Ficus colubrinae diet
(2022)Background: Bats are important long-distance dispersers of many tropical plants, yet, by consuming fruits, they may disperse not only the plant’s seeds, but also the mycobiota within those fruits. We characterized the ... -
Fungal Endophytes and Their Bioactive Compounds in Tropical Forests of Costa Rica
(2021-04-15)We present a glimpse of the diversity of endophytic fungi in the tropical forests of Costa Rica and some examples of bioactive compounds obtained from them. We include the characterization of isolates carried out mainly ... -
In vitro studies to evaluate the wound healing properties of Calendula officinalis extracts
(2017)Ethnopharmacological relevance: Calendula officinalis (pot marigold) flower extracts have a long-lasting tradition in ethnopharmacology. Currently, the European Medicines Agency (EMA) has approved its lipophilic and aqueous ...