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Study of the diversity of culturable actinomycetes in the North Pacific and Caribbean coasts of Costa Rica
(2009)
In this study, 137 actinomycetes were isolated from subtidal marine sediments in the North Pacific and Caribbean coasts of Costa Rica. Bioinformatics analysis of the 16S rRNA gene sequences assigned the isolates to 15 ...
Screening of Latin American plants for antiparasitic activities against malaria,Chagas disease, and leishmaniasis
(2010)
In order to explore rationally the medical potential of the plant biodiversity of the Central and South American region as a source of novel antiparasitic molecules, a multinational Organization of American States (OAS) ...
Richness of cultivable endophytic fungi along an altitudinal gradient in wet forests of Costa Rica
(2016-04)
We collected various plant species along an altitudinal gradient ranging from 400 to 2900 m in tropical wet forests of Costa Rica, isolated the associated endophytic fungi, and performed bioinformatic analyses to determine ...
Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
(2016-02-16)
Pathogenic microorganisms often have the ability to attach to a surface, building a complex matrix where they colonize to form a biofilm. This cellular superstructure can display increased resistance to antibiotics and ...
Streptomyces sp. M54: an actinobacteria associated with a neotropical social wasp with high potential for antibiotic production
(2021-01-17)
Abstract Streptomyces symbionts in insects have shown to be a valuable source of new antibiotics. Here,
we report the genome sequence and the potential for antibiotic production of ‘‘Streptomyces sp. M54’’, an Actinobacteria ...
Molecular data indicate that Rhytidhysteron rufulum (ascomycetes, Patellariales) in Costa Rica consists of four distinct lineages corroborated by morphological and chemical characters
(2009)
Rhytidhysteron rufulum is a poorly known, common, pantropical species, capable of utilizing different substrata and occupying diverse habitats, and is the only species of its genus in Costa Rica. We have employed molecular, ...
Fungal Endophytes and Their Bioactive Compounds in Tropical Forests of Costa Rica
(2021-04-15)
We present a glimpse of the diversity of endophytic fungi in the tropical forests of Costa Rica and some examples of bioactive compounds obtained from them. We include the characterization of isolates carried out mainly ...
Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts
(2015-07-06)
As part of the International Cooperative Biodiversity Groups (ICBG) Program, we were interested in identifying biologically active unfolded protein response (UPR) inducing compounds from marine microorganisms isolated from ...
Recolecta de artrópodos para prospección de la biodiversidad en el Área de Conservación Guanacaste, Costa Rica
(Revista de Biología Tropical 52(1): 119-132, 2004, 2004)
This study describes the results and collection practices for obtaining arthropod samples to be studied as potential sources of new medicines in a bioprospecting effort. From 1994 to 1998, 1800 arthropod samples of 6-10 g ...
Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments
(2017)
High-throughput screening and activity-guided purification identified nicoyamycin A, a natural product comprised of an uncommon 3-methyl-1,4-dioxane ring incorporated into a desferrioxamine-like backbone via a spiroaminal ...