Now showing items 1-6 of 6
Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
Pathogenic microorganisms often have the ability to attach to a surface, building a complex matrix where they colonize to form a biofilm. This cellular superstructure can display increased resistance to antibiotics and ...
Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts
Methods to identify the bioactive diversity within natural product extracts (NPEs) continue to evolve. NPEs constitute complex mixtures of chemical substances varying in structure, composition, and abundance. NPEs can ...
Richness of cultivable endophytic fungi along an altitudinal gradient in wet forests of Costa Rica
We collected various plant species along an altitudinal gradient ranging from 400 to 2900 m in tropical wet forests of Costa Rica, isolated the associated endophytic fungi, and performed bioinformatic analyses to determine ...
Efecto de extractos de artrópodos sobre la multiplicación del Toxoplasma gondiidentro de macrófagos peritoneales de ratón
(Rev. Biol. Trop. 51(2): 317-320, 2003, 2003)
Treatment of toxoplasmosis usually causes secondary effects. It is important to find active substances extracted from natural organisms. In this work we studied some arthropod extracts that have effect against Toxoplasma ...
Costa rican international cooperative biodiversity group: using insects and other arthropods in biodiversity prospecting
In: J. Rosenthal (Ed.). Drug discovery, economic development and conservation: The International Cooperative Biodiversity Groups. Pharm. Biol. Vol 37, Supplement, pp. 55-68.
(Pharmaceutical Biology 37(Supplement):55–68. 1999, 1999)
This paper describes the Costa Rican International Collaborative Biodiversity Group (ICBG), which was designed to introduce insects and other arthropods as a source of pharmaceutical compounds, and to generate knowledge ...
Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A
Three new diketopiperazines (1–3), cyclo(l-Pro-d-trans-Hyp) (1), cyclo(l-Pro-d-Glu) (2), and cyclo(d-Pro-d-Glu) (3) and five known diketopiperazines (4–8) were isolated from the endolichenic fungus Colpoma sp. CR1465A ...