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Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes
The distribution of 125I-labelled Bothrops asper myotoxin following i.m. and i.v. injections was studied in mice. After i.m. administration the toxin was concentrated in the injected gastrocnemius muscle, with relatively ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...