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Sobre el genoma humano, la medicina personalizada y el sistema de seguridad social
(2016)
La promesa del proyecto del genoma humano (PGH) fue que iba a transformar radicalmente la práctica médica. Cambiaría el paradigma de “diagnóstico y tratamiento” por el de “predicción de riesgo y prevención”. Hace más de ...
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)
Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...
Neuropsychological Test Performance in Cognitively Normal Spanish-speaking Nonagenarians with Little Education
(2016-06)
To find associations of age, sex, and education with neuropsychological test performance in cognitively normal Spanish-speaking Costa Rican nonagenarians with little education; to provide norms; and to compare their ...
Genetic diversity in Oryza glumaepatula wild rice populations in Costa Rica and possible gene flow from O. sativa
(2016-04-07)
Wild crop relatives are an important source of genetic diversity for crop improvement. Diversity estimates are generally lacking for many wild crop relatives. The objective of the present study was to analyze how genetic ...
Deletion of amelotin exons 3–6 is associated with amelogenesis imperfecta
(2016-07-12)
Amelogenesis imperfecta (AI) is a heterogeneous group of genetic conditions that result in defective dental enamel formation. Amelotin (AMTN) is a secreted protein thought to act as a promoter of matrix mineralization in ...
A microbial consortium from a biomixture swiftly degrades high concentrations of carbofuran in fluidized-bed reactors
(2016)
An on-farm biopurification system (BPS) biomixture, with proven capacity to degrade carbofuran (CBF) was used as inoculum for a selective-enrichment process to obtain a bacterial consortium capable of using CBF as a sole ...
Molecular characterization and genetic diversity of Jatropha curcas L. in Costa Rica
(2017-02-09)
We estimated the genetic diversity of 50 Jatropha curcas samples from the Costa Rican germplasm bank using 18 EST-SSR, one G-SSR and nrDNA-ITS markers. We also evaluated the phylogenetic relationships among samples using ...
Cellulose-Enriched Microbial Communities from Leaf-Cutter Ant (Atta colombica) Refuse Dumps Vary in Taxonomic Composition and Degradation Ability
(2016-03-21)
Deconstruction of the cellulose in plant cell walls is critical for carbon flow through ecosystems and for the production of sustainable cellulosic biofuels. Our understanding of cellulose deconstruction is largely limited ...