Listar Química por autor "de Lorenzo, Víctor"
Mostrando ítems 1-6 de 6
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A Metabolic Widget Adjusts the Phosphoenolpyruvate-Dependent Fructose Influx in Pseudomonas putida
Chavarría Vargas, Max; Goñi Moreno, Ángel; de Lorenzo, Víctor; Nikel Mayer, Pablo Iván (2016)Fructose uptake in the soil bacterium Pseudomonas putida occurs through a canonical phosphoenolpyruvate (PEP)-dependent sugar transport system (PTSFru). The logic of the genetic circuit that rules its functioning is puzzling: ... -
ArsH protects Pseudomonas putida from oxidative damage caused by exposure to arsenic
Páez Espino, David Antonio; Nikel Mayer, Pablo Iván; Chavarría Vargas, Max; de Lorenzo, Víctor (2020-03-23)The two As resistance arsRBC operons of Pseudomonas putida KT2440 are followed by a downstream gene called arsH that encodes an NADPH‐dependent flavin mononucleotide reductase. In this work, we show that the arsH1 and (to ... -
Concomitant prediction of environmental fate and toxicity of chemical compounds
García Martín, Juan Antonio; Chavarría Vargas, Max; de Lorenzo, Víctor; Pazos, Florencio (2020)The environmental fate of many functional molecules that are produced on a large scale as precursors or as additives to specialty goods (plastics, fibers, construction materials, etc.), let alone those synthesized by the ... -
Low CyaA expression and anti‐cooperative binding of cAMP to CRP frames the scope of the cognate regulon of Pseudomonas putida
Arce Rodríguez, Alejandro; Nikel Mayer, Pablo Iván; Calles, Belén; Chavarría Vargas, Max; Platero, Raúl; Krell, Tino; de Lorenzo, Víctor (2021-03)Although the soil bacterium Pseudomonas putida KT2440 bears a bona fide adenylate cyclase gene (cyaA), intracellular concentrations of 30,50-cyclic adenosine monophosphate (cAMP) are barely detectable. By using reporter ... -
Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress
Nikel Mayer, Pablo Iván; Fuhrer, Tobias; Chavarría Vargas, Max; Sánchez Pascuala, Alberto; Sauer, Uwe; de Lorenzo, Víctor (2021-01-11)As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous oxidative stress. Yet, the ultimate ... -
Transcriptional control of 2,4-dinitrotoluene degradation in Burkholderia sp. R34 bears a regulatory patch that eases pathway evolution
Pérez Pantoja, Danilo; Nikel Mayer, Pablo Iván; Chavarría Vargas, Max; de Lorenzo, Víctor (2021-05)The dnt pathway of Burkholderia sp. R34 is in the midst of an evolutionary journey from its ancestral, natural substrate (naphthalene) towards a new xenobiotic one [2,4-dinitrotoluene (DNT)]. The gene cluster encoding ...