Now showing items 1-3 of 3

    • Bioassay-guided isolation of anti-inflammatory O-sulfated withanolides from Acnistus arborescens (Solanaceae) 

      Steinbrueck, Clara; Mora Ugalde, Nohelia; Morales Sánchez, Carlos; Loaiza Montoya, Randall; García Piñeres, Alfonso J.; Araya Barrantes, Juan José (2019)
      Bioassay-guided fractionation of Acnistus arborescens (Solanaceae) organic extract afforded two anti-inflammatory withanolides: 2,3-Dihydro-3β-O-sulfate withacnistin (1) and 2,3-Dihydro-3β-O-sulfate withaferin A (2) showing ...
    • Pristine but metal-rich Río Sucio (Dirty River) is dominated by Gallionella and other iron-sulfur oxidizing microbes 

      Arce Rodríguez, Alejandro; Puente Sánchez, Fernando; Avendaño Vega, Roberto; Libby Hernández, Eduardo; Rojas Sánchez, Leonardo; Cambronero Heinrichs, Juan Carlos; Pieper, Dietmar H.; Timmis, Kenneth N.; Chavarría Vargas, Max (2017-03)
      Whether the extreme conditions of acidity and heavy metal pollution of streams and rivers originating in pyritic formations are caused primarily by mining activities or by natural activities of metal-oxidizing microbes ...
    • The Bacterial Product Violacein Exerts an Immunostimulatory Effect Via TLR8 

      Venegas Solís, Francisco A.; Köllisch, Gabriele; Mark, Kerstin; Diederich, Wibke E.; Kaufmann, Andreas; Bauer, Stefan; Chavarría Vargas, Max; Araya Barrantes, Juan José; García Piñeres, Alfonso J. (2019)
      Violacein, an indole-derived, purple-colored natural pigment isolated from Chromobacterium violaceum has shown multiple biological activities. In this work, we studied the effect of violacein in different immune cell lines, ...