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Synthesis and Determination of Antibacterial Activity of Jacaranone and Synthetic Analogs
(2017)
Natural product jacaranone, 1, and five more analog derivatives were synthesized and its antibacterial activity against
Gram-positive and Gram-negative microorganisms was tested. One of these derivatives, 5, ...
Isolation of Major Components from the Roots of Godmania aesculifolia and Determination of Their Antifungal Activities
(2013)
From the methanol root extract of Godmania aesculifolia, a species selected in a multinational OAS program aimed at discovering antifungal compounds from Latin American plants, a new chavicol diglycoside (1), the known ...
Low CyaA expression and anti‐cooperative binding of cAMP to CRP frames the scope of the cognate regulon of Pseudomonas putida
(2021-03)
Although the soil bacterium Pseudomonas putida
KT2440 bears a bona fide adenylate cyclase gene
(cyaA), intracellular concentrations of 30,50-cyclic
adenosine monophosphate (cAMP) are barely detectable.
By using reporter ...
Estudio Químico de la Solanacea Markea Megalandra D'Arcy, Aislamiento de escopoletina de sus flores
(1981)
La solanacea Markea megalandra (Dun) D´Arcy se extiende desde Chiapas (México) hasta Venezuela, creciendo en las tierras altas (1900 metros sobre el nivel del mar). El material estudiado se recolectó en las faldas del ...
Análisis de residuos de plomo en repollo de Costa Rica
(1984)
Lead residues analysis in cabbage. Cabbage and soil samples from the main cabbage growing areas of Costa Rica were analyzed for lead residues. Lead residues result from the use of lead arseniate as an insecticide and ...
Phenolic compounds as antiangiogenic CMG2 inhibitors from costa rican endophytic fungi
(2012)
Targeting and inhibiting CMG2 (Capillary Morphogenesis Gene protein 2) represents a new strategy for therapeutic agents for cancer and retinal diseases due to CMG2’s role in blood vessel growth (angiogenesis). A high ...
Bioprospecting
(2001)
Bioprospecting is the systematic search for genes, natural compounds designs and whole organisms in wild life with a potential for product development by biological observation and biophsical, biochemical, and genetic ...
Caracterización de la interacción con el ADN y de las propiedades proinflamatorias de nanopartículas de hidroxiapatitas modificadas
(2020)
La hidroxiapatita (Hap) es un ortofosfato de calcio que constituye el principal componente
mineral de los mamíferos y se encuentra presente en huesos, dientes, piel y tendones. Este
compuesto ha sido utilizado ampliamente ...
Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts
(2014)
Biochemical high-throughput screening is widely used in drug discovery, using a variety of small molecule libraries. However, broader screening strategies may be more beneficial to identify novel biologic mechanisms. In ...
Naproxen degradation test to monitor Trametes versicolor activity in solid-state bioremediation processes
(2010-07-15)
The white-rot fungus Trametes versicolor has been studied as a potential agent for the removal of envi ronmental pollutants. For long-time solid-phase bioremediation systems a test is required to monitor the
metabolic ...