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dc.creatorOtero Patiño, Rafael
dc.creatorNúñez Rangel, Vitelbina
dc.creatorGutiérrez, José María
dc.creatorRobles, Abel
dc.creatorEstrada Umaña, Ricardo
dc.creatorOsorio, Raúl Guillermo
dc.creatorDel Valle, G.
dc.creatorValderrama, R.
dc.creatorGiraldo, Cesar Augusto
dc.date.accessioned2016-12-15T20:18:16Z
dc.date.available2016-12-15T20:18:16Z
dc.date.issued1997-04
dc.identifier.issn0100-879X
dc.identifier.urihttp://hdl.handle.net/10669/29411
dc.description.abstractThree horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atr-ox from Antioquia and Choco (Colombia). The following antivenoms were used: a) polyvalent (crotaline) antivenom produced by Institute Clodomiro Picado (Costa Rica), b) monovalent antibothropic antivenom produced by Institute Nacional de Salud-INS (Bogota), and c) a new monovalent anti-B. atrox antivenom produced with the venom of B. atrox from Antioquia and Choco. The three antivenoms neutralized all toxic activities tested albeit with different potencies. The new monovalent anti-B. atrox antivenom showed the highest neutralizing ability against edema-forming and defibrinating effects of B. atrox venom (41 +/- 2 and 100 +/- 32 mu l antivenom/mg venom, respectively), suggesting that it should be useful in the treatment of B. atrox envenomation in Antioquia and Choco.es_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceBrazilian Journal of Medical and Biological Research; Volumen 30, Número 3, 1997es_ES
dc.subjectBothrops Atroxes_ES
dc.subjectNeutralizationes_ES
dc.subjectAntioquiaes_ES
dc.subjectChocóes_ES
dc.subjectSnake venomes_ES
dc.titleNeutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: Comparison with two commercial antivenomses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1590/S0100-879X1997000300011
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES


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