Mostrar el registro sencillo del ítem

dc.creatorAlape Girón, Alberto
dc.creatorLomonte, Bruno
dc.creatorGustafsson, Bjorn
dc.creatorDa Silva, Nelson Jorge
dc.creatorThelestam, Mónica
dc.date.accessioned2017-09-12T21:10:40Z
dc.date.available2017-09-12T21:10:40Z
dc.date.issued1994
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/0041010194903409es_ES
dc.identifier.issn0041-0101
dc.identifier.urihttp://hdl.handle.net/10669/73142
dc.description.abstractThe electrophoretic mobilities of venom components from 15 Micrurus species were studied by polyacrylamide gel electrophoresis. The venoms showed species-specific protein patterns under native (PAGE) or denaturing (urea-PAGE) conditions. However, electrophoretic patterns obtained by SDS-PAGE under reducing conditions were similar. The proteins of all venoms had mol. wts either in the range of 45 to 75 kDa or lower than 14.5 kDa. PAGE and urea-PAGE of single extraction venom samples from 22 M. nigrocinctus nigrocinctus specimens revealed some proteins completely conserved, whereas others exhibited intraspecies variation. Based on ELISA cross-reactivity studies with 11 monoclonal antibodies against M. n. nigrocinctus venom, venoms from M. n. nigrocinctus, M. nigrocinctus mosquitensis, M. fulvius fulvius, M. dumerilii carnicauda and M. albicinctus were included in the same antigenic group, whereas M. frontalis frontalis and M. frontalis braziliensis venoms constituted a second group. Micrurus alleni and M. spixii spixii showed reactivity patterns similar to groups 1 and 2, respectively. Venoms from M. surinamensis surinamensis, M. corallinus, M. ibiboboca, M. hemiprichii ortoni, M. lemniscatus helleri and M. mipartitus had unique cross-reactivity patterns with monoclonal antibodies against M. n. nigrocinctus venom.es_ES
dc.description.sponsorshipUniversidad de Costa Rica/[741-90-049]/UCR/Costa Ricaes_ES
dc.description.sponsorshipSwedish Agency for Research Cooperation with Developing Countries//SAREC/Sueciaes_ES
dc.description.sponsorshipConsejo Nacional para Investigaciones Científicas y Tecnológicas de Costa Rica//CONICIT/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceToxicon 32(6), 713-723. 1994es_ES
dc.subjectMicruruses_ES
dc.subjectSnake venomes_ES
dc.titleElectrophoretic and immunochemical studies of Micrurus venomses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1016/0041-0101(94)90340-9
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.pmid7940577


Ficheros en el ítem

Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem