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dc.creatorLee, Seulah
dc.creatorTamayo Castillo, Giselle
dc.creatorPang, Changhyun
dc.creatorClardy, Jon
dc.creatorCao, Shugeng
dc.creatorKim, Ki Hyun
dc.date.accessioned2018-04-09T16:12:47Z
dc.date.available2018-04-09T16:12:47Z
dc.date.issued2016-05-15
dc.identifier.citationhttps://www.sciencedirect.com/science/article/pii/S0960894X16303468?via%3Dihubes_ES
dc.identifier.issn0960-894X
dc.identifier.urihttp://hdl.handle.net/10669/74427
dc.description.abstractThree new diketopiperazines (1–3), cyclo(l-Pro-d-trans-Hyp) (1), cyclo(l-Pro-d-Glu) (2), and cyclo(d-Pro-d-Glu) (3) and five known diketopiperazines (4–8) were isolated from the endolichenic fungus Colpoma sp. CR1465A identified from the Costa Rican plant Henriettea tuberculosa (Melatomataceae). The structures of the new compounds 1–3 were elucidated using a combination of extensive spectroscopic analyses, including 2D NMR and HR-MS, and their absolute configurations were determined by a combination of NOESY analysis and Marfey’s method. Cyclo(l-Pro-d-allo-Thr) (4) was recently isolated from a South China Sea marine sponge Callyspongia sp., but its NMR spectroscopic data were not reported, and cyclo(l-Pro-l-Asp) (5) was previously reported but only as a synthetic product. The NMR data assignments of compounds 4 and 5 are reported for the first time. All of the isolated compounds were tested for antifungal and antimicrobial properties.es_ES
dc.description.sponsorshipSEOK CHUN Research Fund-Sungkyunkwan University/[]/SKKU/Coreaes_ES
dc.language.isoen_USes_ES
dc.sourceBioorganic & Medicinal Chemistry Letters, Vol. 26(10), pp.2438-2441es_ES
dc.subjectColpoma sp.es_ES
dc.subjectHenriettea tuberculosaes_ES
dc.subjectDiketopiperazineses_ES
dc.subjectMarfey’s methodes_ES
dc.titleDiketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465Aes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1016/j.bmcl.2016.03.115
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones en Productos Naturales (CIPRONA)es_ES
dc.identifier.pmid27080179


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