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Effect of exposition to chlorpyrifos upon plasmatic cholinesterases, hematology and blood biochemistry values in Bothrops asper (Serpentes: Viperidae)
dc.creator | Arguedas Porras, Randall | |
dc.creator | Gómez Argüello, Aarón | |
dc.creator | Barquero Arroyo, Marco David | |
dc.creator | Chacón Gutiérrez, Danilo | |
dc.creator | Corrales Chaves, Greivin | |
dc.creator | Hernández, Sonia M. | |
dc.creator | León Montero, Guillermo | |
dc.date.accessioned | 2020-11-04T17:26:12Z | |
dc.date.available | 2020-11-04T17:26:12Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | https://www.sciencedirect.com/science/article/abs/pii/S0045653518307604?via%3Dihub#! | |
dc.identifier.issn | 0045-6535 | |
dc.identifier.uri | https://hdl.handle.net/10669/81806 | |
dc.description.abstract | The terciopelo (Bothrops asper), is one of the most important venomous snakes in Costa Rica and common on agriculture where insecticides are frequently used for pest control. To assess the exposure to organophosphates on captive B. asper, an experiment using chlorpyrifos and butyrylcholinesterase (BChE), as a biomarker was conducted. In addition to BChE, hematology, aspartate aminotransferase (AST), total proteins (TP) and albumin were measured after exposure. Different concentrations of chlorpyrifos were used in Group A (0.1%) and B (1%), while the Control Group received distilled water; each group was composed of 5 snakes. Values of BChE, AST, TP, and albumin were measured before exposure, and at 6, 12, 24, 196, 360 and 528 h post-exposure. Hematology values were measured after 24 h post-exposure. As result, an important variation between subjects in all groups before exposure was obtained. Moreover, BChE activity showed 37% inhibition of Group A when compared to Control Group at 12 h post-exposure, and a higher inhibition of Group B (97%) related to Control Group, at 6 h postexposure. Recovery of BChE occurred towards 528 h, never reaching initial values. Despite some variation in the rest of parameters used, a marked relative lymphopenia and monocytosis occurred at 24 h, assuming stress as the main cause. | es_ES |
dc.description.sponsorship | Universidad de Costa Rica/[741-B7-106]/UCR/Costa Rica | es_ES |
dc.language.iso | en_US | es_ES |
dc.source | Chemosphere, vol.205, pp.209-214 | es_ES |
dc.subject | Pesticides | es_ES |
dc.subject | Acetylcholinesterase inhibitors | es_ES |
dc.subject | Bothrops asper | es_ES |
dc.subject | Organophosphates | es_ES |
dc.title | Effect of exposition to chlorpyrifos upon plasmatic cholinesterases, hematology and blood biochemistry values in Bothrops asper (Serpentes: Viperidae) | es_ES |
dc.type | artículo original | |
dc.identifier.doi | 10.1016/j.chemosphere.2018.04.111 | |
dc.description.procedence | UCR::Vicerrectoría de Docencia::Salud::Facultad de Microbiología | es_ES |
dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP) | es_ES |
dc.description.procedence | UCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Biología | es_ES |
dc.description.procedence | UCR::Sedes Regionales::Sede del Caribe::Recinto Limón | es_ES |
dc.identifier.codproyecto | 741-B7-106 |
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