Mostrar el registro sencillo del ítem
Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: Comparison with two commercial antivenoms
dc.creator | Otero Patiño, Rafael | |
dc.creator | Núñez Rangel, Vitelbina | |
dc.creator | Gutiérrez, José María | |
dc.creator | Robles, Abel | |
dc.creator | Estrada Umaña, Ricardo | |
dc.creator | Osorio, Raúl Guillermo | |
dc.creator | Del Valle, G. | |
dc.creator | Valderrama, R. | |
dc.creator | Giraldo, Cesar Augusto | |
dc.date.accessioned | 2016-12-15T20:18:16Z | |
dc.date.available | 2016-12-15T20:18:16Z | |
dc.date.issued | 1997-04 | |
dc.identifier.issn | 0100-879X | |
dc.identifier.uri | https://hdl.handle.net/10669/29411 | |
dc.description.abstract | Three horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atr-ox from Antioquia and Choco (Colombia). The following antivenoms were used: a) polyvalent (crotaline) antivenom produced by Institute Clodomiro Picado (Costa Rica), b) monovalent antibothropic antivenom produced by Institute Nacional de Salud-INS (Bogota), and c) a new monovalent anti-B. atrox antivenom produced with the venom of B. atrox from Antioquia and Choco. The three antivenoms neutralized all toxic activities tested albeit with different potencies. The new monovalent anti-B. atrox antivenom showed the highest neutralizing ability against edema-forming and defibrinating effects of B. atrox venom (41 +/- 2 and 100 +/- 32 mu l antivenom/mg venom, respectively), suggesting that it should be useful in the treatment of B. atrox envenomation in Antioquia and Choco. | es_ES |
dc.description.sponsorship | Universidad de Costa Rica//UCR/Costa Rica | es_ES |
dc.language.iso | en_US | es_ES |
dc.source | Brazilian Journal of Medical and Biological Research; Volumen 30, Número 3, 1997 | es_ES |
dc.subject | Bothrops Atrox | es_ES |
dc.subject | Neutralization | es_ES |
dc.subject | Antioquia | es_ES |
dc.subject | Chocó | es_ES |
dc.subject | Snake venom | es_ES |
dc.title | Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: Comparison with two commercial antivenoms | es_ES |
dc.type | artículo original | |
dc.identifier.doi | 10.1590/S0100-879X1997000300011 | |
dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP) | es_ES |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Microbiología [1171]