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Composition and Gene Expression of the cag Pathogenicity Island in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
dc.creator | Occhialini, Alessandra | |
dc.creator | Marais, Armelle | |
dc.creator | Urdaci, María | |
dc.creator | Sierra Ramos, Rafaela | |
dc.creator | Muñoz Calero, Nubia | |
dc.creator | Covacci, Antonello | |
dc.creator | Mégraud, Francis | |
dc.date.accessioned | 2015-04-17T15:47:18Z | |
dc.date.available | 2015-04-17T15:47:18Z | |
dc.date.issued | 2001-03 | |
dc.identifier.citation | http://iai.asm.org/content/69/3/1902.full | |
dc.identifier.issn | 0019-9567 | |
dc.identifier.uri | https://hdl.handle.net/10669/11387 | |
dc.description | artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2001 | es_ES |
dc.description.abstract | The composition and in vitro expression of the cag pathogenicity island genes in a group of Helicobacter pylori strains obtained from patients suffering from chronic gastritis-associated dyspepsia (n = 26) or gastric carcinoma (it = 17) were analyzed. No significant difference in the distribution of the 10 studied regions was found between the cases and the controls. Nine strains did not harbor any of the selected regions: eight (30.8%) isolated from patients with gastritis only and one (5.9%) from a patient with gastric carcinoma. No association was found between the number of repeated sequences at the 3' end of the cagA gene or the presence of tyrosine phosphorylation motifs and the clinical origin of the strains. The virBIO homolog gene was the sole gene studied to be significantly expressed more often in cancer strains than in gastritis strains (P = 0.03) | es_ES |
dc.description.sponsorship | info:eu-repo/grantAgreement/Universidad de Costa Rica/Instituto de Investigaciones en Salud//Costa Rica// | es_ES |
dc.language.iso | es | es_ES |
dc.publisher | Infection Immunity 69 (3) 1902-1908 | es_ES |
dc.source | Infection and Immunity 69(3):1902-1908 | es_ES |
dc.subject | Helicobacter pylori | es_ES |
dc.subject | chronic gastritis-associated | es_ES |
dc.subject | Genética | es_ES |
dc.subject | Genética humana | es_ES |
dc.subject | Genetics | es_ES |
dc.title | Composition and Gene Expression of the cag Pathogenicity Island in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica | es_ES |
dc.type | artículo original | |
dc.identifier.doi | doi: 10.1128/IAI.69.3.1902-1908.2001 | |
dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA) | es_ES |