Listar Ciencias básicas por autor "Yim, Isaiah"
Mostrando ítems 1-2 de 2
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Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis
Tripathi, Ashootosh; Schofield, Michael M.; Chlipala, George E.; Schultz, Pamela J.; Yim, Isaiah; Newmister, Sean A.; Nusca, Tyler D.; Scaglione, Jamie B.; Hanna, Philip C.; Tamayo Castillo, Giselle; Sherman, David H. (2014)Siderophores are high-affinity iron chelators produced by microorganisms and frequently contribute to the virulence of human pathogens. Targeted inhibition of the biosynthesis of siderophores staphyloferrin B of Staphylococcus ... -
Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
Park, Sung Ryeol; Tripathi, Ashootosh; Wu, Jianfeng; Schultz, Pamela J.; Yim, Isaiah; McQuade, Thomas J.; Yu, Fengan; Arevang, Carl Johan; Mensah, Abraham Y.; Tamayo Castillo, Giselle; Xi, Chuanwu; Sherman, David H. (2016-02-16)Pathogenic microorganisms often have the ability to attach to a surface, building a complex matrix where they colonize to form a biofilm. This cellular superstructure can display increased resistance to antibiotics and ...